Accommodating Vaccine Preferences Among Women of Childbearing Age

Details

• Personal Author:
  Czeisler MÉ ; Czeisler, Charles A. ; Howard ME ; Rajaratnam SMW ; Czeisler MÉ ; Czeisler, Charles A. ; Howard ME ; Rajaratnam SMW
• Description:
  After pregnant persons were excluded from the initial trials leading to emergency use authorizations for COVID-19 vaccines in the United States, Gray et al demonstrated robust vaccine-induced immune responses among pregnant women following COVID-19 messenger RNA (mRNA) vaccination (Pfizer-BioNTech and Moderna), with placental and breastmilk immune transfer to neonates. Unfortunately, rare clotting events following Janssen and AstraZeneca COVID-19 vaccination, which have been disproportionately experienced by women of childbearing age, have dampened the enthusiasm for these vaccines. At present, tailored education and vaccine deployment efforts should prioritize pregnant persons to mitigate newly recognized maternal and neonatal health risks following SARS-CoV-2 infection. Moreover, given the fundamental principles of self-determination, personhood, and patient autonomy that underlie informed consent, respecting patients' right to make voluntary and informed healthcare decisions requires that all individuals should be fully informed about the risks and benefits of each vaccine, and - if feasible - provided a choice among the available COVID-19 vaccines. ... We believe that amid this public health crisis, these considerations necessitate that women of childbearing age be afforded a choice among COVID-19 vaccines to reduce elevated adverse vaccination side effects experienced by women of childbearing age, vaccine hesitancy, and the serious risks COVID-19 poses for pregnant women and their children. [Description provided by NIOSH]
• Subjects:
  Communicable Diseases Immune System Infant, Newborn Occupational Health Pregnancy Public Health Safety Safety Management Women
• Keywords:
  Children COVID-19 Immune Reaction Neonates Public Health Safety Monitoring SARS-CoV-2 Vaccines
• ISSN:
  0002-9378
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Volume:
  225
• Issue:
  6
• NIOSHTIC Number:
  nn:20064211
• Citation:
  Am J Obstet Gynecol 2021 Dec; 225(6):697-699
• Contact Point Address:
  Mark É. Czeisler, AB, Department of Psychiatry Brigham and Women's Hospital, Boston, MA
• Email:
  mark.czeisler@fulbrightmail.org
• Federal Fiscal Year:
  2022
• NORA Priority Area:
  Healthcare and Social Assistance ; Healthcare and Social Assistance
• Performing Organization:
  Brigham and Women's Hospital, Boston, Massachusetts
• Peer Reviewed:
  False
• Start Date:
  20190901
• Source Full Name:
  American Journal of Obstetrics and Gynecology
• End Date:
  20230831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a24a77acef8e7008e7d29b09c30b6a9acbb6c5557fc6a315855fbdbf88139398dfd18c1b1db49fa90f4bb4bc4257188adf76c7903d46df8206f94899e9b755dd
• Download URL:
  https://stacks.cdc.gov/view/cdc/222716/cdc_222716_DS1.pdf
• File Type:
  [PDF - 124.69 KB ]