Self-Reported and Accelerometer-Derived Physical Activity Levels and Coronary Artery Calcification Progression in Older Women: Results from the Healthy Women Study

Details

• Personal Author:
  Edmundowicz D ; Gabriel KP ; Hawkins MS ; Janak JC ; Kohl HW III ; Kriska AM ; Kuller LH ; Matthews KA ; Pérez A
• Description:
  Objective: Regardless of the well-supported biological link between PA and atherosclerosis, most previous studies report a null association between PA and CAC. To examine the relation between physical activity (PA) and coronary artery calcification (CAC) progression in 148 Healthy Women Study (HWS) participants over 28 years of observation. Methods: The HWS was designed to examine cardiovascular risk factor changes from pre- to post-menopause. Based on CAC scores collected at two follow-up visits (EBT1 and EBT4) scheduled 12 years apart, participants were classified into one of three groups: 1) no detectable CAC (n=37; 0 CAC at both visits), 2) incident CAC (n=46; 0 CAC at the first- and >0 CAC at the last-visit), or 3) prevalent CAC (n=65; >0 CAC at both visits). PA data were collected regularly throughout the study using self-report questionnaires and accelerometers at EBT4. Results: The percentage of HWS participants with no detectible CAC decreased from 56.1% at EBT1 to 25.0% at EBT4. Time spent per day in accumulated and bouts of moderate- to vigorous-intensity (MV)PA were each significantly higher in the no detectable CAC group when compared to the prevalent CAC group (both p=.01). After covariate adjustment, these differences remained statistically significant (both p<.05). Although self-reported summary estimates collected throughout the study were significantly associated with accelerometer data at EBT4, there were no significant differences in self-reported physical activity levels by CAC groups after covariate adjustment. Conclusions: Study findings suggest that low levels of accelerometer-derived MVPA may be indicative of subclinical disease in older women. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Occupational Health Safety Surveys And Questionnaires Women
• Keywords:
  Activity Levels Ambulatory Monitoring Author Keywords: Coronary Heart Disease Cardiac Function Cardiovascular System Disorders Coronary Calcification Heart Long Term Study Motion Studies Motor Activity Physical Exercise Questionnaires

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• ISSN:
  1072-3714
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; OSHA Region 6 ; Pennsylvania ; Texas
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  152-161
• Volume:
  20
• Issue:
  2
• NIOSHTIC Number:
  nn:20064146
• Citation:
  Menopause 2013 Feb; 20(2):152-161
• Contact Point Address:
  Kelley Pettee Gabriel, School of Public Health, Division of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center at Houston, Austin Regional Campus, 1616 Guadalupe Street, Suite 6.300, Austin, TX 78701
• Email:
  Kelley.P.Gabriel@uth.tmc.edu
• Federal Fiscal Year:
  2013
• Performing Organization:
  University of Texas Health Science Center, Houston
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Menopause: Journal of the North American Menopause Society
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d1ca435bd016ebabdda54e9665d13119ffcfd458f32b50af06f3a49695704ccae7ec83e60162f0a46f9af8dea23bc3dff9c8e2a17bd0977aa4edbe397dbd15da
• Download URL:
  https://stacks.cdc.gov/view/cdc/222654/cdc_222654_DS1.pdf
• File Type:
  [PDF - 222.45 KB ]