Occupational Physical Activity and Coronary Heart Disease in Women’s Health Initiative Observational Study

Details

• Personal Author:
  Allison MA ; De Roos AJ ; Fujishiro K ; Michael YL ; Nassir R ; Seguin RA ; Wallace R ; Wang C
• Description:
  Background: Women comprise nearly half of the labor force in our society, but the impact of the occupational psychical activity on women's heart health in later life was unclear. We conducted a case-cohort study to assess the association of occupational physical activity, alone and jointly with leisure-time physical activity, and risk of coronary heart disease (CHD). Method: We included women enrolled in Women's Health Initiative Observational Study who provided an occupational history at baseline and were followed until 2013 for the first occurrence of myocardial infarction or CHD death (mean age+/-SD=63.4+/-7.2). 5,243 women free of CHD at baseline were randomly selected into a subcohort and 3,421 CHD events were adjudicated during follow-up. Through linkage of Standard Occupational Classification codes to the Occupational Information Network, we assessed cumulative and most recent exposure of occupational physical activity (OPA). Leisure time physical activity (LTPA) was assessed through WHI's physical activity questionnaire. Weighted Cox proportional hazard models were used to evaluate CHD risk. Results: After adjustment for demographic and socio-economic factors, levels of OPA were not associated with CHD risk. Compared to women with low OPA and high LTPA, women with moderate to high cumulative OPA and low LTPA had relative high CHD risk (HR: 1.54, 95% CI: 1.26, 1.88 for moderate OPA and HR: 1.46. 95% CI: 1.20, 1.78 for high OPA). Discussion: Results from this study suggest no overall association between lifetime OPA and CHD risk in women, but the impact of OPA varies by LTPA levels. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Case Reports Cohort Studies Occupational Health Safety Surveys And Questionnaires Women
• Keywords:
  Activity Levels Author Keywords: Lifetime Cardiovascular Disease Cardiovascular System Cardiovascular System Disease Case Studies Cohort Studies Heart Disease Leisure Time Life Stages Myocardial Disorders Occupations Physical Exercise Physical Fitness Questionnaires Risk Assessment

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• ISSN:
  1079-5006
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  California ; Iowa ; New York ; Ohio ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 5 ; OSHA Region 7 ; OSHA Region 9 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  74
• Issue:
  12
• NIOSHTIC Number:
  nn:20054196
• Citation:
  J Geront, Ser A Biol Sci Med Sci 2019 Dec; 74(12):1952-1958
• Contact Point Address:
  Yvonne L. Michael, ScD, SM, Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, 3215 Market Street, Philadelphia, PA 19104
• Email:
  ylm23@drexel.edu
• Federal Fiscal Year:
  2020
• Peer Reviewed:
  True
• Source Full Name:
  The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:760886e95dfc39bfff050a3d8cc4ce453b3eccd58e9d3589fc20a9fd1d146f96c1353ce030edbf28d13e7198c09c1c0f73cf7119d8e1492fa6ed4f2a2535beba
• Download URL:
  https://stacks.cdc.gov/view/cdc/216808/cdc_216808_DS1.pdf
• File Type:
  [PDF - 229.01 KB ]