PM2.5 and Diabetes and Hypertension Incidence in the Black Women’s Health Study

Details

• Personal Author:
  Brook RD ; Burnett RT ; Coogan PF ; Jerrett M ; Palmer JR ; Rosenberg L ; Seto E ; White LF ; Yu J ; Brook RD ; Burnett RT ; Coogan PF ; Jerrett M ; Palmer JR ; Rosenberg L ; Seto E ; White LF ; Yu J
• Description:
  Background: Clinical studies have shown that exposure to fine particulate matter (PM2.5) can increase insulin resistance and blood pressure. The epidemiologic evidence for an association of PM2.5 exposure with the incidence of type 2 diabetes or hypertension is inconsistent. Even a modest association would have great public health importance given the ubiquity of exposure and high prevalence of the conditions. Methods: We used Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for incident type 2 diabetes and hypertension associated with exposure to PM2.5 in a large cohort of African American women living in 56 metropolitan areas across the US, using data from the Black Women's Health Study. Pollutant levels were estimated at all residential locations over follow-up with a hybrid model incorporating land use regression and Bayesian Maximum Entropy techniques. Results: During 1995 to 2011, 4,387 cases of diabetes and 9,570 cases of hypertension occurred. In models controlling for age, questionnaire cycle, and metro area, there were positive associations with diabetes (HR = 1.13, 95% CI = 1.04, 1.24) and hypertension (HR = 1.06, 95% CI = 1.00, 1.12) per interquartile range of PM2.5 (2.9 microg/m3). Multivariable HRs, however, were 0.99 (95% CI = 0.90, 1.09) for diabetes and 0.99 (95% CI = 0.93, 1.06) for hypertension. Conclusions: Our results provide little support for an association of PM2.5 with diabetes or hypertension incidence. [Description provided by NIOSH]
• Subjects:
  Air Pollution Blood Cardiovascular Diseases Cardiovascular System Cohort Studies Epidemiology Hematologic Diseases Occupational Health Particulate Matter Safety Women

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• Keywords:
  Air Pollution Blood Sugar Disorders Cardiovascular Disease Cohort Studies Health Effects Hypertension Particulates
• ISSN:
  1044-3983
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  California ; Massachusetts ; Michigan ; OSHA Region 1 ; OSHA Region 10 ; OSHA Region 5 ; OSHA Region 9 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Pages in Document:
  202-210
• Volume:
  27
• Issue:
  2
• NIOSHTIC Number:
  nn:20063695
• Citation:
  Epidemiology 2016 Mar; 27(2):202-210
• Contact Point Address:
  Patricia F. Coogan, Slone Epidemiology Center at Boston University, 1010 Commonwealth Ave., Boston, MA 02215
• Email:
  pcoogan@bu.edu
• Federal Fiscal Year:
  2016
• Performing Organization:
  University of Washington
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Epidemiology
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:ae09a61770c0481a78ec0f7442e732f6efbaea8a255166c9c772ffd03cffa1990691d0f84d8b0d9646530526935119bdaf931e937391c7a4a4fff0860a743a02
• Download URL:
  https://stacks.cdc.gov/view/cdc/222256/cdc_222256_DS1.pdf
• File Type:
  [PDF - 289.17 KB ]