Neuromotor Effects of Manganese Exposure in Adolescents Entering Workforce

Details

• Personal Author:
  McBride D
• Description:
  Evidence from recent epidemiological studies suggests childhood Mn exposure causes subclinical developmental neurotoxicity. However there is limited knowledge on the longitudinal impact of childhood Mn exposure. This is the first longitudinal study of Mn exposed children to evaluate the long-term impact on gross motor function. Findings from this epidemiological longitudinal cohort study confirm childhood Mn exposure may manifest subclinical developmental neurotoxicity, seen in adolescent. Findings suggest Mn-exposed children as at risk for occupational slips, trips, and fall. This study has implications regarding the research needs identified at the 2016 international Mn conference to revise NIOSH standards for more adequate protection of workers' health and strategies for prevention of Mn toxicity R2P: Study results identify Mn-exposed children living near a ferromanganese refinery as an at risk population for occupational safety problems. To improve future occupational safety, exposed children should undergo interventions such as balance training to mitigate risk of falls, slips and trips in the workplace. [Description provided by NIOSH]
• Subjects:
  Accidental Falls Accidents Biomarkers Environmental Exposure Manganese Nervous System Occupational Health Safety
• Keywords:
  Children Exposure Levels Longitudinal Study Neuromotor Function Neurotoxic Agents Slips, Trips, And Falls STF
• Publisher:
  University of Cincinnati
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Proceedings
• Place as Subject:
  Kentucky ; Ohio ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-10
• NIOSHTIC Number:
  nn:20058629
• Citation:
  20th Annual Pilot Research Project Symposium, University of Cincinnati Education and Research Center, October 10-11, 2019, Cincinnati, Ohio. Cincinnati, OH: University of Cincinnati, 2019 Oct; :1-10
• CAS Registry Number:
  Manganese (CAS RN 7439-96-5)
• Federal Fiscal Year:
  2020
• Performing Organization:
  University of Cincinnati
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  20th Annual Pilot Research Project Symposium, University of Cincinnati Education and Research Center, October 10-11, 2019, Cincinnati, Ohio
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:83af4dde927503b86d949dfc98330b2d5665e2a5c6f7878a795e76118eca3cb6ccc57decee4e94b92125c273af7848086c8d4919c3b7258ec88fd55928237bc9
• Download URL:
  https://stacks.cdc.gov/view/cdc/221671/cdc_221671_DS1.pdf
• File Type:
  [PDF - 1.61 MB ]