Work Area Measurements as Predictors of Personal Exposure to Endotoxin and Cotton Dust in the Cotton Textile Industry

Details

• Personal Author:
  Astrakianakis G ; Camp J ; Checkoway, Harvey ; Christiani, David C. ; Dai HL ; Eisen EA ; Mehta AJ ; Seixas, Noah S. ; Wang XR
• Description:
  Objectives: To determine if work area measurements of endotoxin and/or cotton dust obtained from the vertical elutriator (VE) can be used to predict levels of personal endotoxin exposure as measured by the Institute of Occupational Medicine (IOM) inhalable dust sampler in the cotton textile industry. Methods: Fifty-six work area cotton dust samples were collected from 14 areas and 82 personal cotton dust samples were collected from 41 workers in three textile mills (Mills A, B and C) in Shanghai, China. Cotton dust concentrations were determined gravimetrically from sample filters, of which endotoxin concentrations were determined using a kinetic chromogenic modification of the limulus amoebocyte lysate assay. Linear regression models were used to determine the association between log IOM personal endotoxin concentration and log VE area endotoxin concentration. Results: Median cotton dust and endotoxin concentrations measured from VE area samples in the three mills were 0.36 mg m-3 and 1280.76 endotoxin units per cubic meter (EU m-3), respectively, compared to 1.74 mg m-3 and 2226.83 EU m-3 from IOM personal samples. Excluding samples from weaving processes, we observed linear associations between VE area measures of endotoxin and IOM personal endotoxin concentrations; VE area concentration of endotoxin explained 83 and 89% of the total variation in IOM personal endotoxin concentration for Mills A and B, respectively (Mill A: R2 = 0.83, P < 0.0001; Mill B: R2 = 0.89, P < 0.0001). Although area measures of cotton dust was also a significant predictor of person endotoxin, the model explained less of the variance in personal endotoxin measurements. Conclusions: Specific to the conditions of the textile mills investigated in this study, work area measurements of endotoxin, but not cotton dust, may be reasonable proxies for personal levels, at least for rank-ordering exposures. [Description provided by NIOSH]
• Subjects:
  Dust Endotoxins Occupational Health Safety Textile Industry
• Keywords:
  Author Keywords: Cotton Dust Cotton Dust Dust Exposure Endotoxin Exposure Assessment Occupational Exposure Shanghai Textile Workers Textiles Industry Textile Workers
• ISSN:
  0003-4878
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1 ; OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  45-54
• Volume:
  52
• Issue:
  1
• NIOSHTIC Number:
  nn:20058450
• Citation:
  Ann Occup Hyg 2008 Jan; 52(1):45-54
• Contact Point Address:
  D. C. Christiani, Department of Environmental Health, Environmental and Occupational Medicine and Epidemiology Program, Harvard School of Public Health, Boston, MA
• Email:
  dchris@hsph.harvard.edu
• Federal Fiscal Year:
  2008
• NORA Priority Area:
  Manufacturing
• Performing Organization:
  Harvard University
• Peer Reviewed:
  True
• Start Date:
  19870701
• Source Full Name:
  Annals of Occupational Hygiene
• End Date:
  20220831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f4ec97955461aee074995c044924882e10c872561d4cb6468b81db9a18cf6ef0c6a7d62c7d596c10ecaba4383eb9db85e1c1fc40cd1caff53654b35e93f7dd4f
• Download URL:
  https://stacks.cdc.gov/view/cdc/221541/cdc_221541_DS1.pdf
• File Type:
  [PDF - 159.71 KB ]