Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Jones, Jeremy C. ; Sonnberg, Stephanie ; Koçer, Zeynep A. ; Shanmuganatham, Karthik ; Seiler, Patrick ; ... More +
Jones, Jeremy C. ; Sonnberg, Stephanie ; Koçer, Zeynep A. ; Shanmuganatham, Karthik ; Seiler, Patrick ; Shu, Yuelong ; Zhu, Huachen ; Guan, Yi ; Peiris, Malik ; Webby, Richard J. ; Webster, Robert G. Less -
Description:
Avian-origin influenza A(H7N9) recently emerged in China, causing severe human disease. Several subtype H7N9 isolates contain influenza genes previously identified in viruses from finch-like birds. Because wild and domestic songbirds interact with humans and poultry, we investigated the susceptibility and transmissibility of subtype H7N9 in these species. Finches, sparrows, and parakeets supported replication of a human subtype H7N9 isolate, shed high titers through the oropharyngeal route, and showed few disease signs. Virus was shed into water troughs, and several contact animals seroconverted, although they shed little virus. Our study demonstrates that a human isolate can replicate in and be shed by such songbirds and parakeets into their environment. This finding has implications for these birds' potential as intermediate hosts with the ability to facilitate transmission and dissemination of A(H7N9) virus.
Subject:
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Animals
Humans
Influenza, Human/epidemiology
Influenza, Human/transmission
Influenza A Virus, H7N9 Subtype
Influenza In Birds/epidemiology
Influenza In Birds/transmission
Parakeets/virology
Research
Songbirds/virology
Virus Replication
Virus Shedding
Water Microbiology

Source:
Emerg Infect Dis. 20(3):380-385.
Document Type:
Journal Article
Place as Subject:
China
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:e9bef2b9ce65655d5a85af04a0db7da1b77eb803cc18268fc84321eb208fe9b5
File Type:

Supporting Files

• 	13-1271-F.gif	gif
  	13-1271-F.jpg	jpeg
  	13-1271.nxml	txt
  	license.txt	txt

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