Mechanisms by Which Metals Promote Events Connected to Neurodegenerative Diseases

Details

• Personal Author:
  Bondy SC ; Campbell A ; Perry G ; Sayre LM ; Smith MA
• Description:
  Although the exact causative phenomenon responsible for the onset and progression of neurodegenerative disorders is at present unresolved, there are some clues as to the mechanisms underlying these chronic diseases. This review addresses mechanisms by which endogenous or environmental factors, through interaction with redox active metals, may initiate a common cascade of events terminating in neurodegeneration. [Description provided by NIOSH]
• Subjects:
  Chronic Disease Metals Occupational Health Oxidants Safety
• Keywords:
  Brain Disorders Chronic Diseases Health Effects Neurological System Oxidative Processes Transition Metals
• ISSN:
  0361-9230
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Ohio ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  125-132
• Volume:
  55
• Issue:
  2
• NIOSHTIC Number:
  nn:20058052
• Citation:
  Brain Res Bull 2001 May; 55(2):125-132
• Contact Point Address:
  Arezoo Campbell, Department of Community and Environmental Medicine, University of California, Irvine, Irvine, CA 92697-1825, USA
• Email:
  aghadimi@uci.edu
• Federal Fiscal Year:
  2001
• Performing Organization:
  University of California, School of Public Health, Los Angeles, CA
• Peer Reviewed:
  True
• Start Date:
  19990701
• Source Full Name:
  Brain Research Bulletin
• End Date:
  20040630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7aa340fe03221c7dfef3976b504d47473b7d2ff68a5c1999a20063a48edb581f98e3f7b25cc3b79e07664cafebfa3148e0db940866856d797a5b102d1e07ec51
• Download URL:
  https://stacks.cdc.gov/view/cdc/221239/cdc_221239_DS1.pdf
• File Type:
  [PDF - 216.87 KB ]