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Targeted testing and the diagnosis of latent tuberculosis infection and tuberculosis disease
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  • Description:
    Background-- Objectives-- New terms-- Reading material: Targeted testing; Diagnosis of LTBI; Diagnosis of TB disease -- Summary-- Additional resources-- Answers to study questions-- Case study answers.

    The Self-Study Modules on Tuberculosis are a series of educational modules designed to provide information about TB in a self-study format. The series consists of a total of nine modules that are separated into two courses. The first course, Modules 1-5, provides basic information on TB. The second course, Modules 6-9, provides more specific TB programmatic information.

    In this module, you will learn about the diagnosis of TB disease and latent TB infection (LTBI), including targeted testing. Targeted testing is a TB control strategy that is used to identify people at high risk for developing TB disease who would benefit by treatment of LTBI, if detected. LTBI is diagnosed with the Mantoux tuberculin skin test (TST) or an interferon-gamma release assay (IGRA) such as the QuantiFERON®-TB Gold test (QFT-G). In most cases, TB disease is diagnosed with certain laboratory tests (bacteriologic examination); for patients who may have pulmonary TB disease, a chest x-ray is also useful for diagnosis. It is important to evaluate people who have symptoms of TB disease; if they are found to have TB disease, they need treatment to be cured and to avoid spreading TB to others. For this reason, the diagnosis of TB disease is crucial to controlling the spread of TB in homes and communities.

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