Epidemiologic and Genomic Evaluation of Influenza D Among Cattle Workers and Their Community

Details

• Personal Author:
  Leibler JH
• Description:
  In this study, we evaluated nasal carriage of influenza D virus among cattle workers employed at industrial dairies in the United States. Influenza D was first documented in cattle and pigs in 2015, and little is known about the ability of this novel and emerging virus to infect humans. To address this gap, we conducted prospective, cross-shift sampling of 31 workers employed at five large-herd dairy operations in two states to assess IDV nasal carriage over a five-day period. We found evidence of IDV in the nasal washes of 67% of participants at least once during the five day study period. IDV exposure was not associated with respiratory symptoms in these workers and the majority of carriage was transient. These findings underscore the need to study IDV spillover to humans through continued study of cattle workers, who are a frontline workforce in the context of emerging zoonotic respiratory diseases. As a K01 award, this award also supported three years of valuable training and mentorship for Dr. Leibler. Due to this support, she successfully competed for an NIH R01 award during the K01 period and is engaged across multiple NIH-supported studies at the present time. [Description provided by NIOSH]
• Subjects:
  Agriculture Communicable Diseases Dairy Products Influenza, Human Livestock Occupational Health Respiratory System Respiratory Tract Diseases Safety Viral Diseases
• Keywords:
  Animal Handlers Animal Husbandry Workers Cattle Dairy Products Emerging Infectious Diseases Influenza Livestock Industry Respiratory Diseases Viral Diseases Zoonoses
• Series:
  Grant Final Reports
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Final Grant Report
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-12
• NIOSHTIC Number:
  nn:20065729
• Citation:
  Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, K01-OH-011432, 2022 Mar; :1-12
• Contact Point Address:
  Jessica H Leibler, BA, DPH, MS, Boston University Medical Campus, 85 East Newton Street, M-921, Boston, MA 02118-2841
• Email:
  jleibler@bu.edu
• Federal Fiscal Year:
  2022
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  Boston University Medical Campus
• Peer Reviewed:
  False
• Start Date:
  20180901
• Source Full Name:
  National Institute for Occupational Safety and Health
• End Date:
  20210831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a36a69b8245a9842061af3cd2f8e86ff3080f7a8857b9ac6f6de2d3069e9ec38e4f1c6acf0fd9bf04cde319cebaa42a31ae913f46af77644cf0798212020d057
• Download URL:
  https://stacks.cdc.gov/view/cdc/219119/cdc_219119_DS1.pdf
• File Type:
  [PDF - 506.02 KB ]