Novel Paramyxovirus Associated with Severe Acute Febrile Disease, South Sudan and Uganda, 2012

Albariño, César G.; Foltzer, Michael; Towner, Jonathan S.; Rowe, Lory A.; Campbell, Shelley; Jaramillo, Carlos M.; Bird, Brian H.; Reeder, DeeAnn M.; Vodzak, Megan E.; Rota, Paul; Metcalfe, Maureen G.; Spiropoulou, Christina F.; Knust, Barbara; Vincent, Joel P.; Frace, Michael A.; Nichol, Stuart T.; Rollin, Pierre E.; Ströher, Ute

doi:10.3201/eid2002.131620

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Novel Paramyxovirus Associated with Severe Acute Febrile Disease, South Sudan and Uganda, 2012

Feb 2014
By Albariño, César G. ; Foltzer, Michael ; Towner, Jonathan S. ; ...
http://dx.doi.org/10.3201/eid2002.131620
Source: Emerg Infect Dis. 20(2):211-216.

[PDF-538.75 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Albariño, César G. ; Foltzer, Michael ; Towner, Jonathan S. ; Rowe, Lory A. ; Campbell, Shelley ; ... More +

Albariño, César G. ; Foltzer, Michael ; Towner, Jonathan S. ; Rowe, Lory A. ; Campbell, Shelley ; Jaramillo, Carlos M. ; Bird, Brian H. ; Reeder, DeeAnn M. ; Vodzak, Megan E. ; Rota, Paul ; Metcalfe, Maureen G. ; Spiropoulou, Christina F. ; Knust, Barbara ; Vincent, Joel P. ; Frace, Michael A. ; Nichol, Stuart T. ; Rollin, Pierre E. ; Ströher, Ute Less -
Description:

In 2012, a female wildlife biologist experienced fever, malaise, headache, generalized myalgia and arthralgia, neck stiffness, and a sore throat shortly after returning to the United States from a 6-week field expedition to South Sudan and Uganda. She was hospitalized, after which a maculopapular rash developed and became confluent. When the patient was discharged from the hospital on day 14, arthralgia and myalgia had improved, oropharynx ulcerations had healed, the rash had resolved without desquamation, and blood counts and hepatic enzyme levels were returning to reference levels. After several known suspect pathogens were ruled out as the cause of her illness, deep sequencing and metagenomics analysis revealed a novel paramyxovirus related to rubula-like viruses isolated from fruit bats.
Subjects:

[+]

Acute Disease Adult Animals Chiroptera Female High-Throughput Nucleotide Sequencing Humans Molecular Sequence Annotation Paramyxoviridae Infections Paramyxovirinae Phylogeny Research Rna, Viral Travel
Source:

Emerg Infect Dis. 20(2):211-216.
Pubmed ID:

24447466
Pubmed Central ID:

PMC3901491
Document Type:

Journal Article
Place as Subject:

South Sudan ; Sudan ; Uganda

South Sudan ; Sudan ; Uganda Less -
Location:

Africa
Volume:

20
Issue:

2
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:00ab15c6eb9324f4dec5426cdd318168f3521ed55a35cffc6b8c025459942a6a
Download URL:

https://stacks.cdc.gov/view/cdc/21738/cdc_21738_DS1.pdf
File Type:

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