Anncaliia algerae Microsporidial Myositis

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Watts, Matthew R. ; Chan, Renee C.F. ; Cheong, Elaine Y.L. ; Brammah, Susan ; Clezy, Kate R. ; Tong, Chiwai ; Marriott, Deborah ; Webb, Cameron E. ; Chacko, Bobby ; Tobias, Vivienne ; Outhred, Alexander C. ; Field, Andrew S. ; Prowse, Michael V. ; Bertouch, James V. ; Stark, Damien ; Reddel, Stephen W.
• Description:
  The insect microsporidian Anncaliia algerae was first described in 2004 as a cause of fatal myositis in an immunosuppressed person from Pennsylvania, USA. Two cases were subsequently reported, and we detail 2 additional cases, including the only nonfatal case. We reviewed all 5 case histories with respect to clinical characteristics, diagnosis, and management and summarized organism life cycle and epidemiology. Before infection, all case-patients were using immunosuppressive medications for rheumatoid arthritis or solid-organ transplantation. Four of the 5 case-patients were from Australia. All diagnoses were confirmed by skeletal muscle biopsy; however, peripheral nerves and other tissues may be infected. The surviving patient received albendazole and had a reduction of immunosuppressive medications and measures to prevent complications. Although insects are the natural hosts for A. algerae, human contact with water contaminated by spores may be a mode of transmission. A. algerae has emerged as a cause of myositis, particularly in coastal Australia.
• Subjects:
  Aged Apansporoblastina Arthritis, Rheumatoid Australia Fatal Outcome Humans Immunocompromised Host Immunosuppressive Agents Life Cycle Stages Male Microsporidiosis Muscle, Skeletal Myositis Organ Transplantation

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• Source:
  Emerg Infect Dis. 20(2):185-191.
• Document Type:
  Journal Article
• Place as Subject:
  Australia
• Volume:
  20
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:36608e82edada4426a1f44996873979053fe56a2a25f2db52f5585a69b4e3147
• Download URL:
  https://stacks.cdc.gov/view/cdc/21725/cdc_21725_DS1.pdf
• File Type:
  [PDF - 441.10 KB ]