New Causes of Occupational Asthma

Details

• Corporate Authors:
  Michigan State University. College of Human Medicine
• Description:
  Each year new agents that cause occupational asthma are published in the medical literature. The current list of known causes of occupational asthma includes over 400 substances ((http://www.haz-map.com/OA1.html)) or ((http://www.aoecdata.org/ExpCodeLookup.aspx)). Routinely asking adult patients with new-onset asthma about possible work-related triggers is the initial step in identifying these new agents. Most publications in the medical literature on new causes are case reports which include a description of the patient's symptoms, exposure, documentation of hyperreactivity, skin testing and some form of pulmonary function testing specific to the exposure or workplace. This issue of Project SENSOR News reviews the new agents identified as causing occupational asthma in 2010. Agents are divided into high molecular weight proteins from animals and plants where sensitization is typically through an IgE-mediated mechanism and low molecular weight chemicals that act as a hapten and bind with a protein in the patient. Sensitization with these chemical agents is typically not IgE mediated. A review article was published in 2011 that also included new asthmagens reported in 2009 (Quirce S, Sastre J, 2011). [Description provided by NIOSH]
• Subjects:
  Asthma, Occupational Epidemiology Lung Diseases Occupational Exposure Occupational Health Respiratory Tract Diseases Safety
• Keywords:
  Lung Disease Occupational Asthma Occupational Exposure Surveillance
• Publisher:
  Michigan State University-College of Human Medicine
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Newsletter
• Place as Subject:
  Michigan ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-4
• Volume:
  22
• Issue:
  3
• NIOSHTIC Number:
  nn:20054549
• Citation:
  Project S.E.N.S.O.R. News 2011 May; 22(3):1-4
• Contact Point Address:
  MSU-CHM, 117 West Fee Hall, East Lansing, MI 48824-1316
• Federal Fiscal Year:
  2011
• Performing Organization:
  Michigan State University
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  Project S.E.N.S.O.R. News
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6b19d4326f64256296747b055ad8a20742d023f4213d102911567548fe5276e4f787cc9ef70135bd1c08e7c1eddbb43d3ef28b51583af849f78e56c76025b5dd
• Download URL:
  https://stacks.cdc.gov/view/cdc/217077/cdc_217077_DS1.pdf
• File Type:
  [PDF - 194.76 KB ]