The Relationships Between Blood Lead Levels and Serum Thyroid Stimulating Hormone and Total Thyroxine in the Third National Health and Nutrition Examination Survey

Details

• Personal Author:
  Krieg EF Jr.
• Description:
  Regression analysis was used to estimate and test for relationships between the blood lead concentration and the concentrations of serum thyroid stimulating hormone and serum total thyroxine in adults, 20 years and older, participating in the third National Health and Nutrition Examination Survey. No relationship was found between the blood lead level and the concentration of serum thyroid stimulating hormone. The serum total thyroxine concentration decreased as the blood lead level increased in women, but not in men. The lowest concentration of blood lead at which a relationship could be detected was 2.1 µg/dL and 3.9 µg/dL for the non-pregnant and pregnant women, respectively. Hypothetical mechanisms of the action of lead are discussed. [Description provided by NIOSH]
• Subjects:
  Endocrine System Lead Men Occupational Health Safety Women
• Keywords:
  Author Keywords: Blood Lead Blood Lead Levels Hormones Humans NHANES III Regression Analysis Thyroid Stimulating Hormone Thyroxine
• ISSN:
  0946-672X
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  130-137
• Volume:
  51
• NIOSHTIC Number:
  nn:20053482
• Citation:
  J Trace Elem Med Biol 2019 Jan; 51:130-137
• Contact Point Address:
  Ed F. Krieg Jr., National Institute for Occupational Safety and Health, Robert A. Taft Laboratories, 1150 Tusculum Avenue, Cincinnati, OH 45226
• Email:
  erk3@cdc.gov
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  2019
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Trace Elements in Medicine and Biology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:85e5f094c1583445b39245c946d3610e4421ff0e79ac751704d101c515f617b6362af0be388e8c44bb61bdfcc14f3690e70deba0782382c56ecd24b329dd4628
• Download URL:
  https://stacks.cdc.gov/view/cdc/216226/cdc_216226_DS1.pdf
• File Type:
  [PDF - 1.23 MB ]