Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Richter, Sandra S. ; Heilmann, Kristopher P. ; Dohrn, Cassie L. ; Riahi, Fathollah ; Diekema, Daniel J. ; ... More +
Richter, Sandra S. ; Heilmann, Kristopher P. ; Dohrn, Cassie L. ; Riahi, Fathollah ; Diekema, Daniel J. ; Doern, Gary V. Less -
Description:
Serotyping data for pneumococci causing invasive and noninvasive disease in 2008-2009 and 2010-2011 from >43 US centers were compared with data from preconjugate vaccine (1999-2000) and postconjugate vaccine (2004-2005) periods. Prevalence of 7-valent pneumococcal conjugate vaccine serotypes decreased from 64% of invasive and 50% of noninvasive isolates in 1999-2000 to 3.8% and 4.2%, respectively, in 2010-2011. Increases in serotype 19A stopped after introduction of 13-valent pneumococcal vaccine (PCV13) in 2010. Prevalences of other predominant serotypes included in or related to PCV13 (3, 6C, 7F) also remained similar for 2008-2009 and 2010-2011. The only major serotype that increased from 2008-2009 to 2010-2011 was nonvaccine serotype 35B. These data show that introduction of the 7-valent vaccine has dramatically decreased prevalence of its serotypes and that addition of serotypes in PCV13 could provide coverage of 39% of isolates that continue to cause disease.
Subject:
[+]
Adolescent
Adult
Aged
Age Distribution
Anti-Bacterial Agents
Child
Child, Preschool
Cluster Analysis
Humans
Infant
Microbial Sensitivity Tests
Middle Aged
Penicillin Resistance
Penicillins
Pneumococcal Infections
Pneumococcal Vaccines
Prevalence
Serotyping
Vaccines, Conjugate
Young Adult

Source:
Emerg Infect Dis. 19(7):1074-1083.
Document Type:
Journal Article
Place as Subject:
United States
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:3ffdddf5c0f1a5654f2a8b739cc5779774967db0cbde944402ce42203c8c30ff
File Type:

Supporting Files

• 	12-1830-F.gif	gif
  	12-1830-F.jpg	jpeg
  	12-1830.nxml	txt
  	license.txt	txt

More +