Occupationally Related Hypersensitivity Lung Disease in Israeli Veterinarians

Details

• Personal Author:
  Bar-Sela S ; Baum GL ; Lutsky I ; Mazar A ; Teichntahl H ; Toshner D
• Description:
  200 veterinarians (V) were studied to identify a relationship between occupational exposure to animals and the presence of clinical hypersensitivity. History of respiratory symptoms and animal exposure was elicited from each subject. Prick skin testing was performed using common inhalant antigens and a broad screen of animal antigens. Blood was assayed for total and specific IgE and for precipitating antibodies to fungal and animal antigens. Simple pulmonary function testing (PFT) was done. A control group of 100 subjects (Cl with no occupational animal exposure was similarly studied. 43/198(V) were positive on skin testing of which 25 (12.6%) reacted to animal antigens. For (C) 17/100 reacted of which 9/100 reacted to animal antigens. 45/200 (V) had allergic respiratory and/or eye symptoms in 23 of which (11.5%) these symptoms were animal related. Among 100 (C) 20 had allergic respiratory and/or eye symptoms in 4 of which animal relationship was clear. A total of 18 (V) out of 79 tested had abnormal PFT (13 restrictive pattern, 5 obstructive, while 15 (C) of 99 tested had abnormal PFT (13 restrictive pattern, 2 obstructive). It appears as if professional exposure to animals in the group of Israeli veterinarians tested (approximately 2/3 of the entire professional group) is not associated with the development of excess allergic respiratory disease. Although (V) and (C) were similar in age and smoking habits more abnormalities of pulmonary function were found in (V). The reasons for these findings are not clear. [Description provided by NIOSH]
• Subjects:
  Fungi Health Personnel Hypersensitivity Occupational Health Respiratory Tract Diseases Safety Veterinarians
• Keywords:
  Allergens Allergic Reactions Allergies Animal Handlers Fungal Diseases Fungal Infections Humans Respiratory System Disorders
• ISSN:
  0003-0805
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  125
• Issue:
  4
• NIOSHTIC Number:
  nn:20052910
• Citation:
  Am Rev Respir Dis 1982 Apr; 125(4)(Pt 2)(Suppl):160
• Federal Fiscal Year:
  1982
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  Chaim Sheba Medical Center, Tel Hashomer, Israel
• Peer Reviewed:
  True
• Part Number:
  2
• Start Date:
  19790701
• Source Full Name:
  American Review of Respiratory Disease
• Supplement:
  S
• End Date:
  19820630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0f93acad5367cc78ed73a2af7dc32652cc03de64d6b352e789d071b85abf869e09ddf00bbaf61453f6d15f7e3338c1d6f2ac54d71ab3373d912e901fbd385688
• Download URL:
  https://stacks.cdc.gov/view/cdc/215816/cdc_215816_DS1.pdf
• File Type:
  [PDF - 289.28 KB ]