Urinary 8-Hydroxy-2′-Deoxyguanosine as a Biomarker of Oxidative DNA Damage in Workers Exposed to Fine Particulates

Christiani, David C.; Kim JY; Mukherjee S; Ngo LC

i

Urinary 8-Hydroxy-2′-Deoxyguanosine as a Biomarker of Oxidative DNA Damage in Workers Exposed to Fine Particulates

2004/05/01
By Christiani, David C. ; Kim JY ; Mukherjee S ; ...

Details

Personal Author:

Christiani, David C. ; Kim JY ; Mukherjee S ; Ngo LC
Description:

Residual oil fly ash (ROFA) is a chemically complex mixture of compounds, including metals that are potentially carcinogenic because of their ability to cause oxidative injury. In this study, we investigated the association between exposure to particulate matter with an aerodynamic mass median diameter
Subjects:

Aging Air Pollutants, Occupational Biomarkers Carcinogens Chemistry Environmental Exposure Lead Manganese Metals Nickel Occupational Health Oxidants Particulate Matter Risk Assessment Risk Factors Safety Smokers Urine Vanadium
Keywords:

Age Groups Author Keywords: Biomarkers Bronchitis Chemical Composition Chemical Properties Deoxyribonucleic Acids DNA DNA Damage Epidemiology Exposure Levels Fumes Humans Injuries Models Occupational Oxidative DNA Damage Oxidative Processes Particulate Matter Particulates Risk Factors Sampling Smoking Statistical Analysis Urine Chemistry
ISSN:

0091-6765
Document Type:

Text
Funding:

Grant
Genre:

Journal Article
Place as Subject:

Massachusetts ; OSHA Region 1
CIO:

National Institute for Occupational Safety and Health (NIOSH)
Topic:

Workplace Safety & Health
Location:

North America
Volume:

112
Issue:

6
NIOSHTIC Number:

nn:20057340
Citation:

Environ Health Perspect 2004 May; 112(6):666-671
Contact Point Address:

D.C. Christiani, Harvard School of Public Health, Occupational Health Program, Building I, Room 1402, 665 Huntington Ave., Boston, MA 02115
Email:

dchris@hohp.harvard.edu
CAS Registry Number:

Lead (CAS RN 7439-92-1) ; Manganese (CAS RN 7439-96-5) ; Nickel (CAS RN 7440-02-0) ; Vanadium (CAS RN 7440-62-2)
Federal Fiscal Year:

2004
Performing Organization:

Harvard School of Public Health, Boston, Massachusetts
Peer Reviewed:

True
Start Date:

19980701
Source Full Name:

Environmental Health Perspectives
End Date:

20030630
Collection(s):

National Institute for Occupational Safety and Health
Main Document Checksum:

urn:sha-512:4e51d746b0364b9f42570d140b158455be6f3b19262654a889c52f3e7d81619080dcc142c8c85217a56d94f34507b9059cdd67d6999cf6bf9239efca44839e1a
Download URL:

https://stacks.cdc.gov/view/cdc/214725/cdc_214725_DS1.pdf
File Type:

[PDF - 129.03 KB ]

ON THIS PAGE

Details

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.