Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement from the American Heart Association

Details

• Personal Author:
  Bhatnagar A ; Brook JR ; Brook RD ; Diez-Roux AV ; Holguin F ; Hong Y ; Kaufman JD ; Luepker RV ; Mittleman MA ; Peters A ; Pope CA III ; Rajagopalan S ; Siscovick D ; Smith SC Jr ; Whitsel L
• Corporate Authors:
  American Heart Association. Council on Epidemiology and Prevention ; American Heart Association. Council on the Kidney in Cardiovascular Disease ; American Heart Association. Council on Nutrition, Physical Activity and Metabolism
• Description:
  In 2004, the first American Heart Association scientific statement on "Air Pollution and Cardiovascular Disease" concluded that exposure to particulate matter (PM) air pollution contributes to cardiovascular morbidity and mortality. In the interim, numerous studies have expanded our understanding of this association and further elucidated the physiological and molecular mechanisms involved. The main objective of this updated American Heart Association scientific statement is to provide a comprehensive review of the new evidence linking PM exposure with cardiovascular disease, with a specific focus on highlighting the clinical implications for researchers and healthcare providers. The writing group also sought to provide expert consensus opinions on many aspects of the current state of science and updated suggestions for areas of future research. On the basis of the findings of this review, several new conclusions were reached, including the following: Exposure to PM <2.5 um in diameter (PM2.5) over a few hours to weeks can trigger cardiovascular disease-related mortality and nonfatal events; longer-term exposure (eg, a few years) increases the risk for cardiovascular mortality to an even greater extent than exposures over a few days and reduces life expectancy within more highly exposed segments of the population by several months to a few years; reductions in PM levels are associated with decreases in cardiovascular mortality within a time frame as short as a few years; and many credible pathological mechanisms have been elucidated that lend biological plausibility to these findings. It is the opinion of the writing group that the overall evidence is consistent with a causal relationship between PM2.5 exposure and cardiovascular morbidity and mortality. This body of evidence has grown and been strengthened substantially since the first American Heart Association scientific statement was published. Finally, PM2.5 exposure is deemed a modifiable factor that contributes to cardiovascular morbidity and mortality. [Description provided by NIOSH]
• Subjects:
  Air Pollution Cardiovascular Diseases Cardiovascular System Morbidity Mortality Occupational Health Particulate Matter Safety
• Keywords:
  Air Pollution Atherosclerosis Author Keywords: AHA Scientific Statements Cardiovascular Disease Epidemiology Health Effects Heart Disease Morbidity Rates Mortality Rates Particulates Prevention Public Policy

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• ISSN:
  0009-7322
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Georgia ; Kentucky ; Massachusetts ; Michigan ; Minnesota ; New Hampshire ; North Carolina ; OSHA Region 1 ; OSHA Region 10 ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 6 ; OSHA Region 8 ; OSHA Region 9 ; Texas ; Utah ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  121
• Issue:
  21
• NIOSHTIC Number:
  nn:20057236
• Citation:
  Circulation 2010 Jun; 121(21):2331-2378
• Federal Fiscal Year:
  2010
• Performing Organization:
  University of Washington
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Circulation
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:be468543d5d8ae1b91bad31e7209494fa665ee22551412fe812f39ba3836812a0a8b688acb67dfca189eeed7a7aa414ce54c7f2b7fe7e836788c69912f9927f3
• Download URL:
  https://stacks.cdc.gov/view/cdc/214655/cdc_214655_DS1.pdf
• File Type:
  [PDF - 703.78 KB ]