Environmental Tobacco Smoke and Parkinson’s Disease

Details

• Personal Author:
  Checkoway, Harvey ; Franklin GM ; Gallagher LG ; Longstreth WT Jr. ; Lundin JI ; Searles Nielsen S ; Smith-Weller T ; Swanson PD
• Description:
  Background: Parkinson's disease is inversely associated with cigarette smoking, but its relation with passive smoking or environmental tobacco smoke exposure is rarely examined. Methods: Within a case-control study, we assessed the association between Parkinson's disease and living or working with active smokers. Cases were newly diagnosed with idiopathic Parkinson's disease (n = 154) from western Washington State in 2002-2008. Age- and sex-matched controls (n = 173) were neurologically normal and unrelated to cases. Results: Compared with never active or passive tobacco smokers, we observed reduced Parkinson's disease risks for ever passive only smokers (OR, 0.34; 95% CI, 0.16-0.73), similar to those for ever active smokers (OR, 0.35; 95% CI, 0.17-0.73). Among persons whose only tobacco smoke exposure was passive smoking at home, risk was inversely associated with years exposed. Conclusions: These observations parallel those well established for active smoking. However, it remains unresolved whether a true protective effect of tobacco smoke, generally detrimental to health, underlies these associations. [Description provided by NIOSH]
• Subjects:
  Environmental Exposure Nervous System Nervous System Diseases Occupational Health Safety Smoke Smokers Tobacco Products
• Keywords:
  Author Keywords: Environmental Tobacco Smoke Pollution Environmental Exposure Idiopathic Parkinson's Disease Neurological Disorders Parkinsons Disease Passive Smoking Smoking Tobacco Smoke
• ISSN:
  1531-8257
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  293-296
• Volume:
  27
• Issue:
  2
• NIOSHTIC Number:
  nn:20057162
• Citation:
  Mov Disord 2012 Feb; 27(2):293-296
• Contact Point Address:
  Susan Searles Nielsen, PhD, University of Washington, Department of Environmental and Occupational Health Sciences, Box 357234, Seattle, WA 98195-7234, USA
• Email:
  ssn@u.washington.edu
• Federal Fiscal Year:
  2012
• Performing Organization:
  University of Washington
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Movement Disorders
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:44cfd179d78cde9a1802877bcaa94e9c3b98ed390b22580d304a2accc8741c443b2e993e2e11c9c251e2db3ba1bba626b1b92d857519c16e640f700327223b06
• Download URL:
  https://stacks.cdc.gov/view/cdc/214594/cdc_214594_DS1.pdf
• File Type:
  [PDF - 359.36 KB ]