Determination of Preexcision Surgical Margins of Melanomas from Fixed-Tissue Specimens

Details

• Personal Author:
  Doyle JP ; Golomb FM ; Grin CM ; Kopf AW ; Levenstein MJ ; Silverman MK
• Description:
  The shrinkage of cutaneous surgical specimens of 199 malignant melanomas was analyzed. A formula was derived that makes it possible to calculate the in vivo (preexcision) specimen diameter from the in vitro (fixed-tissue) specimen diameter. The age of the patient was found to significantly influence specimen shrinkage and was incorporated into this shrinkage formula. The calculated in vivo specimen diameter was then used to determine the width of the in vivo surgical margins with reasonable accuracy. Thus this method permits calculation of the width of surgical margins from fixed-tissue specimens. [Description provided by NIOSH]
• Subjects:
  Neoplasms Occupational Health Pathology Safety Skin Skin Diseases
• Keywords:
  Cancer In Vivo Study Skin Cancer Surgery
• ISSN:
  0032-1052
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  88
• Issue:
  5
• NIOSHTIC Number:
  nn:20056957
• Citation:
  Plast Reconstr Surg 1991 Nov; 88(5):804-809
• Contact Point Address:
  Frederick M. Golomb, M.D., Department of Surgery, New York University Medical Center, 560 First Avenue, New York, N.Y. 10016
• Federal Fiscal Year:
  1992
• Performing Organization:
  New York University, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19790401
• Source Full Name:
  Plastic and Reconstructive Surgery
• End Date:
  19820331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6ae51cf04a3c6426f5032ef35cde4302f6711bda49c646152ba731629f92a95b4dd9e60bc3a4bf4af2197e680256be105372a8d4067a6b7bd4aa9cb3c7c096c7
• Download URL:
  https://stacks.cdc.gov/view/cdc/214445/cdc_214445_DS1.pdf
• File Type:
  [PDF - 1.13 MB ]