Expansion of the Performance Capabilities of the USF Inhalation Challenge Chamber

Details

• Personal Author:
  Riley LF
• Description:
  The purpose of this research was to evaluate the capability and performance of the University of South Florida's (USF) Human Exposure Chamber (HEC) using aerosols in the thoracic range. The goals of this research were two-fold: to obtain an average particle size of 10 um (thoracic-size range) inside the chamber during dust production and to test for evenness of dust concentration within the chamber. The USF HEC can be used for studies using gases and/or particulates. The chamber measurements are 4.16 ft × 2.67 ft × 6.75 ft, for a total volume of 75 ft3 or 2.13 m 3. This research has public health significance since outdoor air pollution is found most commonly in the thoracic size range; future studies with the HEC could focus on the impact of outdoor air pollution on human subjects under various exposure conditions, and various particle size ranges. Soda lime glass beads were used in this study due to their uniformity in shape and size. A Wright Dust Feeder (WDF) was used to generate the glass beads aerosol in the chamber. Nitrogen gas and HEPA-filtered fresh air were used to transport the aerosol through the system and into the chamber. A total of nine different chamber configurations were made in order to increase the average particle size closer to the goal of 10 um. Chamber reconfiguration provided statistically significant effect on increasing particle size with the exception of two intermediate settings. It was concluded that aerosol distribution within the chamber was even during operation of the chamber, and modification steps utilized in the study provided size distribution within +/- 6% of the target particle size. [Description provided by NIOSH]
• Subjects:
  Aerosols Air Pollution Occupational Health Particulate Matter Respiratory System Safety
• Keywords:
  Aerosol Aerosol Generation Air Pollution Author Keywords: Inhalation Challenge Exposure Chambers Inhalation Studies Particle Aerodynamics Particle Size Particulate Matter Thoracic-fraction
• ISBN:
  9781369428056
• Publisher:
  ProQuest LLC.
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Dissertation
• Place as Subject:
  Florida ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20056239
• Citation:
  Ann Arbor, MI: ProQuest LLC., 2016 Oct; :10243176
• Federal Fiscal Year:
  2017
• Performing Organization:
  Sunshine Education and Research Center, University of South Florida
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  Expansion of the performance capabilities of the USF inhalation challenge chamber
• End Date:
  20290630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2d0bba780942b3e02218284165a14b0ece657d5f44a2168c711dfddb7d989968b9ac1cad8b53ddc5b45ee101b8d8010ceb8e5f9b984b40f45edae7b7f8f11946
• Download URL:
  https://stacks.cdc.gov/view/cdc/213885/cdc_213885_DS1.pdf
• File Type:
  [PDF - 14.61 MB ]