Contribution of Antimicrobials to the Development of Allergic Disease

Details

• Personal Author:
  Anderson, Stacey E. ; Shane HL ; Weatherly L
• Description:
  Antimicrobials represent a broad class of chemicals with the intended purpose of eliminating or controlling the growth of harmful microorganisms. Exposure can occur occupationally or through the use or consumption of consumer products. The use of antimicrobial agents has been associated with an increased incidence of allergic diseases, including asthma, atopic dermatitis, and less commonly, anaphylaxis. Very diverse immunological mechanisms and mediators have been identified in the sensitization response to antimicrobial chemicals and the importance of the local microenviroment in the response is increasingly being recognized. A complete understanding of the mechanisms of allergic diseases resulting from antimicrobial exposure will help to ensure safe environments and exposure limits. [Description provided by NIOSH]
• Subjects:
  Asthma Dermatitis Environmental Exposure Hypersensitivity Microbiology Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety

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• Keywords:
  Allergic Disorders Anaphylactic Shock Antimicrobials Bronchial Asthma Chemicals Exposure Levels Exposure Limits Microorganisms Risk Factors Sensitization
• ISSN:
  0952-7915
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  91-95
• Volume:
  60
• NIOSHTIC Number:
  nn:20056209
• Citation:
  Curr Opin Immunol 2019 Oct; 60:91-95
• Contact Point Address:
  Stacey E Anderson, National Institute of Occupational Safety and Health, Health Effects Laboratory Division, Allergy and Clinical Immunology Branch, Morgantown, WV, 26508
• Email:
  Sanderson4@cdc.gov
• Federal Fiscal Year:
  2020
• NORA Priority Area:
  Healthcare and Social Assistance
• Peer Reviewed:
  True
• Source Full Name:
  Current Opinion in Immunology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a58f1c7e05bca694d85fd713a197f4d413d3701fe718657d8b61f8f7d533ea3d4cc9b8333ca84ba40fef297bf371bd190ee4f5a1c7cdb5732a36021a5ffc4884
• Download URL:
  https://stacks.cdc.gov/view/cdc/213861/cdc_213861_DS1.pdf
• File Type:
  [PDF - 235.51 KB ]