Air Pollution/Irritants, Asthma Control, and Health-Related Quality of Life Among 9/11-Exposed Individuals with Asthma

Details

• Personal Author:
  Cone, James E. ; Friedman SM ; Li J ; Osahan S ; Yung J
• Description:
  Asthma control is suboptimal among World Trade Center Health Registry (WTCHR) enrollees. Air pollution/irritants have been reported as the most prevalent trigger among World Trade Center responders. We examined the relationship between air pollution/irritants and asthma control. We also evaluated the association of asthma control with health-related quality of life (HRQoL). We included 6202 enrollees age =18 with a history of asthma who completed the WTCHR asthma survey between 2015 and 2016. Based on modified National Asthma Education and Prevention Program criteria, asthma was categorized as controlled, poorly-controlled, or very poorly-controlled. HRQoL indicators include =14 unhealthy days, =14 activity limitation days, and self-rated general health. We used multinomial logistic regression for asthma control, and unconditional logistic regression for HRQoL, adjusting for covariates. Overall, 27.1% had poorly-controlled and 32.2% had very poorly-controlled asthma. Air pollution/irritants were associated with poorly-controlled (adjusted odds ratio (AOR) = 1.70; 95% CI = 1.45-1.99) and very poorly-controlled asthma (AOR = 2.15; 95% CI = 1.83-2.53). Poor asthma control in turn worsened the HRQoL of asthmatic patients. Very poorly-controlled asthma was significantly associated with =14 unhealthy days (AOR = 3.60; 95% CI = 3.02-4.30), =14 activity limitation days (AOR = 4.37; 95% CI = 3.48-5.50), and poor/fair general health status (AOR = 4.92; 95% CI = 4.11-5.89). Minimizing World Trade Center (WTC) asthmatic patients' exposure to air pollution/irritants may improve their disease management and overall well-being. [Description provided by NIOSH]
• Subjects:
  Air Pollution Asthma Environmental Exposure Hazardous Substances Irritants Men Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety September 11 Terrorist Attacks Women

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• Keywords:
  Air Pollution Asthma Author Keywords: 9/11 Disaster Bronchial Asthma Exposure Levels Health-related Quality Of Life Health Hazards Humans Quality Of Life Risk Factors Statistical Analysis Triggers World Trade Center WTC

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• ISSN:
  1660-4601
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  16
• Issue:
  11
• NIOSHTIC Number:
  nn:20056055
• Citation:
  Int J Environ Res Public Health 2019 Jun; 16(11):1924
• Contact Point Address:
  Janette Yung, New York City Department of Health and Mental Hygiene, World Trade Center Health Registry, New York City, NY 10013
• Email:
  jyung@health.nyc.gov
• Federal Fiscal Year:
  2019
• Performing Organization:
  New York City Health/Mental Hygiene
• Peer Reviewed:
  True
• Start Date:
  20090430
• Source Full Name:
  International Journal of Environmental Research and Public Health
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3fd1ac9cf8b514fd5720e88709aa073fa272f5560e969bd121f2be01c454aa248c6f6f3bad84636b1537a39b559f625940943a4aca09f93586f7db7014a146eb
• Download URL:
  https://stacks.cdc.gov/view/cdc/213752/cdc_213752_DS1.pdf
• File Type:
  [PDF - 329.30 KB ]