Permeation of 2-Butoxyethanol Through Disposable Nitrile Gloves

Details

• Personal Author:
  Banaee S ; Que Hee S
• Description:
  Objective: The purpose of this study was to assess the permeation of 2- butoxyethanol (99 percent purity) through disposable, unlined, unsupported, purple nitrile exam glove materials. The goal was to investigate the protective capability and reliability of the gloves during occupational exposures. Methods: This study utilized the American Society for Testing and Materials (ASTM) F739-99a closed-loop permeation method. The glove materials were conditioned for 24 h in a desiccator at a relative humidity of 52 +/- 1 percent at room temperature. The weight and thickness of glove materials were recorded before and after permeation. Four 1inch diameter standard permeation cells (3 experimental cells with 2- butoxyethanol as challenge and one air blank) were used with water as collection solvent. The cells were immersed in a shaking water bath at 35.0 +/- 0.5 C and agitated at an average horizontal shaking speed of 6.9 +/- 0.5 cm/s. Aliquots of 0.1 mL were taken at permeation time intervals of 1 and 10 min, 1, 2, 4, 6, and 8 h. The analytical method was based on gas chromatography-mass spectrometry (GC-MS) using the internal standard method (4bromophenol as internal standard) and selected ion monitoring (m/z 57 and 172) and injection of 2-uL aliquots. Results: The percent differences of the thickness and weight before and after permeation were less than 10 percent. The ASTM normalized breakthrough detection time corresponding to 0.25 ug/cm2 occurred at <1 minute. The permeation stabilized at 9.8 +/- 0.61 ug/cm2 from 4 through 8 hours and the average diffusion coefficient was (7.24 +/- 0.15) ×10-5 cm2/min. Conclusions: The disposable purple nitrile exam gloves have been found to provide no protection against skin exposure to 2- butoxyethanol, since the permeation exceeded the ASTM threshold normalized breakthrough detection time (0.25 ug/cm2 ) in less than a minute, and the steady state permeation rate is classified as not recommended. The gloves should not be used as personal protective equipment for exposure to 2- butoxyethanol even for very short period exposures. [Description provided by NIOSH]
• Subjects:
  Nitriles Occupational Health Personal Protective Equipment Safety
• Keywords:
  2-Butoxyethanol Equipment Testing Gloves PPE
• Publisher:
  American Industrial Hygiene Association
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  72
• NIOSHTIC Number:
  nn:20055836
• Citation:
  AIHce 2014: American Industrial Hygiene Conference and Exposition, May 31 - June 5, 2014, San Antonio, Texas. Falls Church, VA: American Industrial Hygiene Association, 2014 Jun; :72
• CAS Registry Number:
  2-Butoxyethanol (CAS RN 111-76-2)
• Federal Fiscal Year:
  2014
• Performing Organization:
  University of California Los Angeles
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  AIHce 2014: American Industrial Hygiene Conference and Exposition, May 31 - June 5, 2014, San Antonio, Texas
• End Date:
  20270630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b1a43649081b53ce622015bfa6b291759147d42b6dd49471d0f42e7626a2869422c4b970ffe2371192a7ac1fd0df84f1c966275cdd018d8b31238cc36e52b281
• Download URL:
  https://stacks.cdc.gov/view/cdc/213602/cdc_213602_DS1.pdf
• File Type:
  [PDF - 287.74 KB ]