2,4-diaminoanisole (4-methoxy-m-phenylediamine) in hair and fur dyes

doi:10.26616/NIOSHPUB78111

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

i

2,4-diaminoanisole (4-methoxy-m-phenylediamine) in hair and fur dyes

January 13, 1978
By National Institute for Occupational Safety and Health.
Series: NIOSH Numbered Publications

English

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Details:

Alternative Title:

2,4-diaminoanisole (4-methoxy-m-phenylediamine) in hair and fur dyes
Corporate Authors:

National Institute for Occupational Safety and Health.
Description:

NIOSH recommends that 2,4-diaminoanisole (615054), or 4-methoxy-m- phenylenediamine, and its salts be handled in the work place as if they were human carcinogens. This recommendation is based primarily upon a preliminary analysis of the National Cancer Institute data indicating that rats fed 2,4-diaminoanisole experience statistically significant excess of site specific malignant tumors as compared to controls. Caution is also indicated by NIOSH epidemiologic studies which suggest an elevated incidence of cancer among cosmetologists. Exposures should be limited to as few employees as possible, while minimizing workplace exposure levels with engineering and work practice controls. In particular, skin exposures should be avoided.
Subjects:

[+]

Anisoles/toxicity Carcinogens Hair Dyes/toxicity Occupational Exposure/prevention & Control
Series:

NIOSH Numbered Publications
Subseries:

Current Intelligence Bulletin
DOI:

https://doi.org/10.26616/NIOSHPUB78111
Document Type:

Book
Pages in Document:

ii, 5 numbered pages
Volume:

19
NIOSHTIC Number:

00076384
Resource Number:

DHEW (NIOSH) Publication No. 78-111; CIB 19
Collection(s):

National Institute for Occupational Safety and Health
Main Document Checksum:

[+]

urn:sha-512:befdca5a87563fc89bcc77ad75dad3a97d14827d9371143beea7389bcbbbf0e6402356109558dfc62323616460181016e851411db9b16cf5878f45b2449d349f
Download URL:

https://stacks.cdc.gov/view/cdc/21270/cdc_21270_DS1.pdf
File Type:

[PDF-3.06 MB]