Current Intelligence Bulletin 19: 2,4-Diaminoanisole (4-methoxy-m-phenylediamine) in Hair and Fur Dyes

Details

• Alternative Title:
  2,4-diaminoanisole (4-methoxy-m-phenylediamine) in hair and fur dyes
• Journal Article:
  National Institute for Occupational Safety and Health
• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  NIOSH recommends that 2,4-diaminoanisole (615054), or 4-methoxy-m- phenylenediamine, and its salts be handled in the work place as if they were human carcinogens. This recommendation is based primarily upon a preliminary analysis of the National Cancer Institute data indicating that rats fed 2,4-diaminoanisole experience statistically significant excess of site specific malignant tumors as compared to controls. Caution is also indicated by NIOSH epidemiologic studies which suggest an elevated incidence of cancer among cosmetologists. Exposures should be limited to as few employees as possible, while minimizing workplace exposure levels with engineering and work practice controls. In particular, skin exposures should be avoided. [Description provided by NIOSH]
• Subjects:
  Amines Animals Carcinogens Cosmetics Epidemiology Manufacturing And Industrial Facilities Occupational Diseases Occupational Health Safety Safety Management Toxicology

  More +
• Keywords:
  NIOSH-Author; NIOSH-Current-Intelligence-Bulletin-No-19; Carcinogens; Oxidizers; Industrial-hygiene; Epidemiology; Cosmetics-workers; Chemical-industry-workers; Animal-products-workers; Amines; Toxicology; Hairdressers; Occupational-diseases; Safety-measures; Control-methods
• Source:
  Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 78-111 (CIB 19), 1978 Jan; :1-7
• Series:
  NIOSH Numbered Publications
• Subseries:
  Current Intelligence Bulletin
• DOI:
  https://doi.org/10.26616/NIOSHPUB78111
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Report
• Place as Subject:
  Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DCDSD - Division of Criteria Documents and Standards Developments
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  8 pdf pages
• NIOSHTIC Number:
  nn:00076384
• NTIS Accession Number:
  PB-277266
• CAS Registry Number:
  2,4-Diaminoanisole (CAS RN 615-05-4)
• Federal Fiscal Year:
  1978
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:befdca5a87563fc89bcc77ad75dad3a97d14827d9371143beea7389bcbbbf0e6402356109558dfc62323616460181016e851411db9b16cf5878f45b2449d349f
• Download URL:
  https://stacks.cdc.gov/view/cdc/21270/cdc_21270_DS1.pdf
• File Type:
  [PDF - 3.06 MB ]