Effects of Poor and Short Sleep on Glucose Metabolism and Obesity Risk

Details

• Personal Author:
  Leproult R ; Spiegel K ; Tasali E ; Van Cauter E
• Description:
  The importance of sleep to hormones and glucose metabolism was first documented more than four decades ago. Since then, sleep curtailment has become an endemic behavior in modern society. In addition, the prevalence of sleep disorders, particularly obstructive sleep apnea (OSA), has increased. OSA is very common in endocrine and metabolic disorders, but often remains undiagnosed. This Review summarizes the laboratory and epidemiologic evidence that suggests how sleep loss, either behavioral or disease-related, and poor quality of sleep might promote the development of obesity and diabetes mellitus, and exacerbate existing endocrine conditions. Treatment of sleep disorders has the potential to improve glucose metabolism and energy balance. Screening for habitual sleep patterns and OSA might be critically important for patients with endocrine and metabolic disorders. [Description provided by NIOSH]
• Subjects:
  Behavior Blood Epidemiology Hematologic Diseases Occupational Health Safety Sleep Sleep Initiation And Maintenance Disorders
• Keywords:
  Behavior Patterns Blood Sugar Disorders Endocrine System Disorders Hormone Activity Metabolic Disorders Obesity Sleep Deprivation Sleep Disorders
• ISSN:
  1759-5029
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Illinois ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  253-261
• Volume:
  5
• Issue:
  5
• NIOSHTIC Number:
  nn:20052801
• Citation:
  Nat Rev Endocrinol 2009 May; 5(5):253-261
• Contact Point Address:
  K Spiegel, iNSERMM/ UCBL-U628, Physiologie intégrée du système d'eveil, Département de Médecine expérimentale, Faculté de Médecine, Université Claude Bernard Lyon 1, 8 Avenue rockefeller, 69373 Lyon Cedex 08, France
• Email:
  karine.spiegel@univ-lyon1.fr
• Federal Fiscal Year:
  2009
• NORA Priority Area:
  Healthcare and Social Assistance
• Performing Organization:
  University of Chicago
• Peer Reviewed:
  True
• Start Date:
  20090901
• Source Full Name:
  Nature Reviews Endocrinology
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:901f78b33a19f17a37e8f56f48c3faa8c2491487c74d1c41294e0483b1885aacba235882cbdf141a0243c8c8fc83d24551ba8a097188ceba815e6165f5997f24
• Download URL:
  https://stacks.cdc.gov/view/cdc/212274/cdc_212274_DS1.pdf
• File Type:
  [PDF - 283.44 KB ]