Sleep Disturbances and Insulin Resistance

Details

• Personal Author:
  Van Cauter E
• Description:
  The causes and risk factors of insulin resistance remain insufficiently understood. After taking into account the important roles of adiposity, age, sex and race/ethnicity, up to 50% of the individual variability in insulin resistance remains unexplained. In recent years, evidence has accumulated to support a role for sleep disturbances, including insufficient sleep, poor sleep quality and insomnia, and obstructive sleep apnoea, as independent risk factors for the development and exacerbation of insulin resistance. The present review summarizes the evidence. We will start with a brief introduction to sleep and its disorders and then examine in succession the role of the three major types of sleep disturbances of modern society, namely insufficient sleep, poor sleep quality and/or insomnia and obstructive sleep apnoea. Insulin resistance is a hallmark of the polycystic ovary syndrome, the most common endocrine pathology in women, and the last section of this review will discuss the role of obstructive sleep apnoea in the insulin resistance and metabolic disturbances of polycystic ovary syndrome. [Description provided by NIOSH]
• Subjects:
  Blood Hematologic Diseases Occupational Health Safety Sleep Sleep Initiation And Maintenance Disorders Women
• Keywords:
  Author Keywords: Insulin Resistance Blood Sugar Disorders Endocrine System Disorders Hormone Activity Menstrual Disorders Sleep Apnoea Sleep Deprivation Sleep Disorders
• ISSN:
  0742-3071
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Illinois ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  28
• Issue:
  12
• NIOSHTIC Number:
  nn:20052776
• Citation:
  Diabet Med 2011 Dec; 28(12):1455-1462
• Contact Point Address:
  Eve Van Cauter PhD, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, MC 1027, Chicago, IL 60637, USA
• Email:
  evcauter@medicine.bsd.uchicago.edu
• Federal Fiscal Year:
  2012
• NORA Priority Area:
  Healthcare and Social Assistance
• Performing Organization:
  University of Chicago
• Peer Reviewed:
  True
• Start Date:
  20090901
• Source Full Name:
  Diabetic Medicine
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6067a828305f61a041cd4ed5844c89b0e2299d2291dfdd94650a3790c01c4e2d802acff806f0e946c15f4a9023afeae451749d3587589cc2d2e2c5d58f8ad112
• Download URL:
  https://stacks.cdc.gov/view/cdc/212251/cdc_212251_DS1.pdf
• File Type:
  [PDF - 223.06 KB ]