Synergistic Effects of Engineered Nanoparticles and Organics Released from Laser Printers Using Nano-Enabled Toners: Potential Health Implications from Exposures to the Emitted Organic Aerosol

Details

• Personal Author:
  Bello D ; Castranova, Vincent ; Chalbot M-CG ; Demokritou P ; Kasaraneni V ; Kavouras IG ; Oyanedel-Craver V ; Pirela SV ; Qian Y ; Schifman L ; Thomas T
• Description:
  Recent studies have shown that engineered nanoparticles (ENPs) are incorporated into toner powder used in printing equipment and released during their use. Thus, understanding the functional and structural composition and the potential synergistic effects of this complex aerosol and released gaseous co-pollutants is critical in assessing their potential toxicological implications and risks. In this study, toner powder and PEPs were thoroughly examined for the functional and molecular composition of the organic fraction and the concentration profile of 16 Environmental Protection Agency (EPA)-priority polycyclic aromatic hydrocarbons (PAH) using state-of-the-art analytical methods. Results show significant differences in abundance of the non-exchangeable organic hydrogen of toner powder and PEPs, with a stronger aromatic spectral signature in PEPs. Changes in the structural composition of PEPs are indicative of radical additions and free-radical polymerization favored by catalytic reactions, resulting in formation of functionalized organic species. Particularly, accumulation of aromatic carbons with strong styrene-like molecular signatures on PEPs is associated with formation of semi-volatile heavier aromatic species (i.e., PAHs). Further, the transformation of low molecular weight PAHs in the toner powder to high molecular weight PAHs in PEPs was documented and quantified. This may be a result of synergistic effects from catalytic metal/metal oxide ENPs incorporated into the toner and the presence/release of semi-volatile organic species (SVOCs). The presence of known carcinogenic PAHs on PEPs raises public health concerns and warrants further toxicological assessment. [Description provided by NIOSH]
• Subjects:
  Aerosols Hydrocarbons Occupational Health Polycyclic Aromatic Hydrocarbons Printing Safety
• Keywords:
  Metal Oxides Nanoparticles Nanotechnology Polycyclic Aromatic Hydrocarbons Printer-emitted Particles Printers Synergistic Effects Toners
• ISSN:
  2051-8161
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Journal Article
• Place as Subject:
  Alabama ; Maryland ; Massachusetts ; OSHA Region 1 ; OSHA Region 3 ; OSHA Region 4 ; Rhode Island ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  4
• Issue:
  11
• NIOSHTIC Number:
  nn:20050673
• Citation:
  Environ Sci Nano 2017 Nov; 4(11):2144-2156
• Contact Point Address:
  Ilias G.Kavouras, Department of Environmental Health Sciences, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, Alabama 35294
• Email:
  kavouras@uab.edu
• Federal Fiscal Year:
  2018
• Peer Reviewed:
  True
• Source Full Name:
  Environmental Science: Nano
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2411764fdf4e83bfd56d7b0cb74aff68d9b9203911ff1e6b1f6784b8767a767f59c85647e82bf0196ed5b392b94da1389218001e09f045c528beade9e63d326e
• Download URL:
  https://stacks.cdc.gov/view/cdc/210925/cdc_210925_DS1.pdf
• File Type:
  [PDF - 1.52 MB ]