Quality Assurance Considerations for Nanoparticles

Details

• Personal Author:
  Hoover, Mark D. ; Rickabaugh KP
• Description:
  The 5th edition of the AIHA Laboratory Quality Assurance Manual provides a foundation to successfully anticipate, recognize, evaluate, control, and confirm the appropriate development, management, evaluation, and application-specific limitations of a laboratory quality assurance (QA) program in a broad spectrum of situations. The intent of this chapter is to build on the topic-based guidance provided in the other chapters of this manual and to advise sampling and laboratory personnel of special considerations to apply QA concepts for nanomaterial-related measurements. Nanotechnology encompasses broad areas of ongoing and evolving research, development, and applications. Changes are underway that must be continually assessed. The emerging and increasing development and use of numerous types of engineered nanomaterials for a myriad applications such as electronic, pharmaceutical, automotive, and aerospace presents challenges to the effective creation, conduct, and evaluation of a QA program. Challenges in the pharmaceutical industry, for example, include the fact that many historical and established drug formulations were developed using particles in the micrometer and larger size. With the introduction of drug constituents in the nanometer-size range, QA programs are being asked to consider how those nano-formulated materials may need to be collected, handled, or analyzed differently, or may respond in different ways from their larger or bulk materials. [Description provided by NIOSH]
• Subjects:
  Chemistry Hazardous Substances Occupational Health Quality Control Safety
• Keywords:
  Biological Agents Chemical Properties Laboratory Workers Nanomaterials Nanoparticles Nanotechnology Physical Properties Quality Assurance Sampling Surface Properties Toxins

  More +
• ISBN:
  9781935082484
• Publisher:
  American Industrial Hygiene Association
• Document Type:
  Text
• Genre:
  Book
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  RHD - Respiratory Health Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  125-136
• NIOSHTIC Number:
  nn:20050596
• Citation:
  AIHA laboratory quality assurance manual, 5th edition. Teague AL, Eide ME, eds. Falls Church, VA: American Industrial Hygiene Association, 2015 May; :125-136
• Editor(s):
  Teague AL; Eide ME
• Federal Fiscal Year:
  2015
• Peer Reviewed:
  False
• Source Full Name:
  AIHA laboratory quality assurance manual, 5th edition
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f5090ab8609c796db778fd03c213172e8eecd8917cc12d7cf7048911efc8a96b7471feee4141947c5ca12082d3cf62433f79243f532b3f46c5ec30cdca8ee54c
• Download URL:
  https://stacks.cdc.gov/view/cdc/210878/cdc_210878_DS1.pdf
• File Type:
  [PDF - 3.79 MB ]