Lab-on-a-Chip Sensor with Evaporated Bismuth Film Electrode for Anodic Stripping Voltammetry of Zinc

Details

• Personal Author:
  Bange A ; Heineman WR ; Kang W ; Papautsky I ; Pei X ; Yue W
• Description:
  In this work, we report on the development of a lab-on-a-chip electrochemical sensor that uses an evaporated bismuth electrode to detect zinc using square wave anodic stripping voltammetry. The microscale electrochemical cell consists of a bismuth working electrode, an integrated silver/silver chloride reference electrode, and a gold auxiliary electrode. The sensor demonstrated linear response in 0.1 M acetate buffer at pH 6 with zinc concentrations ranging from 1 uM to 30 uM and a calculated detection limit of 60 nM. The sensor was also able to successfully detect zinc in a bovine serum extract and the results were verified with independent AAS measurements. These results demonstrate the advantageous qualities of this lab-on-a-chip electrochemical sensor for clinical applications, which include a small sample volume (uL scale), reduced cost, short response time and high accuracy at low concentrations of analyte. [Description provided by NIOSH]
• Subjects:
  Occupational Health Safety Silver
• Keywords:
  Author Keywords: Anodic Stripping Voltammetry Bismuth Dopamine Electrochemical Properties Evaporated Bi Film Electrode Gold Lab-on-a-chip Sensor Monitoring Systems Silver Compounds Zinc Zinc And Compounds

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• ISSN:
  1040-0397
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  25
• Issue:
  12
• NIOSHTIC Number:
  nn:20050149
• Citation:
  Electroanalysis 2013 Dec; 25(12):2586-2594
• Contact Point Address:
  Ian Papautsky, BioMicroSystems Lab, Department of Electrical Engineering and Computing Systems, University Of Cincinnati, Cincinnati, OH, 45221
• Email:
  ian.papautsky@uc.edu
• CAS Registry Number:
  Gold (CAS RN 7440-57-5) ; Silver (CAS RN 7440-22-4) ; Zinc (CAS RN 7440-66-6)
• Federal Fiscal Year:
  2014
• Performing Organization:
  University of Cincinnati
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Electroanalysis
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c8e32271fd0a822235658fbeac0854d08b6da50ead8e5a1ccc7c86eb06bacc91235fb60a2cc4e5dc96df0a8f0c8fee1912ca6257bdda55dcc0ae0afad912f871
• Download URL:
  https://stacks.cdc.gov/view/cdc/210623/cdc_210623_DS1.pdf
• File Type:
  [PDF - 1.68 MB ]