Flavoring-Related Lung Disease: Information for Healthcare Providers (Superseded)

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  This document has been superseded and the new version can be found here. Severe obstructive lung disease has been identified in people who work with flavoring chemicals containing diacetyl, including butter flavoring. Cases of severe lung disease have occurred in microwave popcorn plants and flavoring production plants. Lung biopsies in some affected people have shown the presence of a rare condition; constrictive bronchiolitis obliterans (also referred to as constrictive bronchiolitis, obliterative bronchiolitis, and bronchiolitis obliterans). In some workers, fixed airways obstruction has been severe enough to be fatal. [Description provided by NIOSH]
• Subjects:
  Chemistry Fibrosis Hypersensitivity Lung Lung Diseases Men Occupational Health Respiratory System Respiratory Tract Diseases Safety Women

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• Keywords:
  Chemical-hypersensitivity Chemical-properties Exposure-levels Exposure-limits Fibrogenicity Humans Lung-disease Lung-disorders Lung-function Lung-irritants Lung-tissue Pulmonary-disorders Pulmonary-system-disorders Respiratory-system-disorders Workers

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• Series:
  NIOSH Numbered Publications
• DOI:
  https://doi.org/10.26616/NIOSHPUB2012107
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Report
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-6
• NIOSHTIC Number:
  nn:20039933
• Citation:
  Morgantown, WV: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2012-107, 2011 Nov; :1-6
• CAS Registry Number:
  Butanedione (CAS RN 431-03-8)
• Federal Fiscal Year:
  2012
• Peer Reviewed:
  False
• Source Full Name:
  National Institute for Occupational Safety and Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:bc710741e61e9b5a4b377da68edf56dbb42dbf4ed848bd6c16b2545187c842ee2e17d96328d2887fd6d9648f6bb81ff9f9af32d16940b9657313fae4bc0db642
• Download URL:
  https://stacks.cdc.gov/view/cdc/209995/cdc_209995_DS1.pdf
• File Type:
  [PDF - 2.52 MB ]