The Effects of Inorganic Lead On Behavioral and Neurologic Function. Final Report

Details

• Personal Author:
  Corum CR ; Garcia LS Jr. ; Jones PD ; Repko JD
• Description:
  Subjects in this study of the effects of lead (7439921) exposure on behavioral and neurologic function were employed in two regions of the United States. Of the 140 workers sampled, 85 workers were exposed to lead in the job and 55 served as comparisons. Each worker who volunteered for the study was subjected to 53 behavioral measures of sensory and motor functioning, six measures of nerve conduction velocity, five indices of inorganic lead absorption, a clinical electromyogram, and a clinical neurological examination. Demographic data were also collected from each participant. The exposed workers were employed in the storage battery manufacturing industry. Based on the data obtained in this study and others, the adverse effects of occupational exposure to inorganic lead (7439921) on certain functional capacities was demonstrated. Quantifiable behavioral and neurological effects were noted at levels below the accepted biologic guideline of 80 micrograms of lead per 100 milliliters of blood. Deficits in the peripheral nerves, in visual reaction time, as well as deficits in auditory functioning were demonstrated. According to the authors, questions concerning the progression of these effects and their reversibility in individual workers must be addressed. [Description provided by NIOSH]
• Subjects:
  Behavior Hazardous Substances Lead Lead Poisoning Manufacturing And Industrial Facilities Mental Disorders Metals, Heavy Nervous System Nervous System Diseases Occupational Health Safety

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• Keywords:
  Battery-manufacturing-industry Behavioral-disorders Contract-210-75-0054 Heavy-metals Lead-poisoning Nervous-system-disorders Neuropathology NIOSH-Contract Toxic-effects
• Series:
  NIOSH Numbered Publications
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Report
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DBBS - Division of Biomedical and Behavioral Sciences
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-102
• NIOSHTIC Number:
  nn:00194416
• NTIS Accession Number:
  PB91-108126
• Citation:
  Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 78-128, 1978 Jan; :1-102
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  1978
• Peer Reviewed:
  False
• Source Full Name:
  National Institute for Occupational Safety and Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1f028669aeb15732c665141da1fb800266b5514505f36ea4112deb2c239f8949370eac8d44f7a880819932ffa19781107600017e71015ad9e358f1852b173816
• Download URL:
  https://stacks.cdc.gov/view/cdc/209583/cdc_209583_DS1.pdf
• File Type:
  [PDF - 3.74 MB ]