Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus

Qiu, Chao; Huang, Yang; Zhang, Anli; Tian, Di; Wan, Yanmin; Zhang, Xiaoling; Zhang, Wanju; Zhang, Zhiyong; Yuan, Zhenghong; Hu, Yunwen; Zhang, Xiaoyan; Xu, Jianqing

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Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus

Published Date:

Oct 2013

Source:

Emerg Infect Dis. 19(10):1685-1687.

[PDF-369.50 KB]

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Alternative Title:

Emerg Infect Dis

Personal Author:

Qiu, Chao ; Huang, Yang ; Zhang, Anli ; Tian, Di ; Wan, Yanmin ; ... More ▼

Description:

Serologic studies are urgently needed to assist in understanding an outbreak of influenza A(H7N9) virus. However, a biosafety level 3 laboratory is required for conventional serologic assays with live lethal virus. We describe a safe pseudovirus-based neutralization assay with preliminary assessment using subtype H7N9-infected samples and controls.

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Document Type:

Journal Article

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Emerging Infectious Diseases

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Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus

Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus

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