Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1909.130299
Personal Author:
Fiebelkorn, Amy Parker ; Lawler, Jacqueline ; Curns, Aaron T. ; Brandeburg, Christina ; Wallace, Gregory S.
Fiebelkorn, Amy Parker ; Lawler, Jacqueline ; Curns, Aaron T. ; Brandeburg, Christina ; Wallace, Gregory S. Less -
Description:
Although the measles-mumps-rubella (MMR) vaccine is not recommended for mumps postexposure prophylaxis (PEP), data on its effectiveness are limited. During the 2009-2010 mumps outbreak in the northeastern United States, we assessed effectiveness of PEP with a third dose of MMR vaccine among contacts in Orthodox Jewish households who were given a third dose within 5 days of mumps onset in the household's index patient. We compared mumps attack rates between persons who received a third MMR dose during the first incubation period after onset in the index patient and 2-dose vaccinated persons who had not. Twenty-eight (11.7%) of 239 eligible household members received a third MMR dose as PEP. Mumps attack rates were 0% among third-dose recipients versus 5.2% among 2-dose recipients without PEP (p=0.57). Although a third MMR dose administered as PEP did not have a significant effect, it may offer some benefits in specific outbreak contexts.
Subject:
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Adolescent Adult Child Child, Preschool Female Humans Immunization Schedule Infant Male Measles-Mumps-Rubella Vaccine Mumps Mumps Virus Post-Exposure Prophylaxis Research Young Adult
Source:
Emerg Infect Dis. 19(9):1411-1417.
Document Type:
Journal Article
Place as Subject:
New York
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:e3b1fa367d974d35b3bdd5976a8859ed58805b83fede8172c5e09c575e62146f
Download URL:
https://stacks.cdc.gov/view/cdc/20898/cdc_20898_DS1.pdf
File Type:

Supporting Files

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