Rat-Tail Models for Studying Hand-Arm Vibration Syndrome: A Comparison Between Living and Cadaver Rat Tails

Details

• Personal Author:
  Chapman P ; Dong, Ren G. ; Jackson M ; Krajnak, Kristine M. ; McKinney WG ; Sensel EW ; Service S ; Warren CM ; Waugh, Stacey ; Welcome DE ; Wu, John Z. ; Xu XS
• Description:
  Over-exposure of the hand-arm system to intense vibration and force over time may cause degeneration of the vascular, neurological, and musculoskeletal systems in the fingers. A novel animal model using rat tails has been developed to understand the health effects on human fingers exposed to vibration and force when operating powered hand tools or workpieces. The biodynamic responses, such as vibration stress, strain, and power absorption density, of the rat tails can be used to help evaluate the health effects related to vibration and force and to establish a dose-effect relationship. While the biodynamic responses of cadaver rat tails have been investigated, the objective of the current study was to determine whether the biodynamic responses of living rat tails are different from those of cadaver rat tails, and whether the biodynamic responses of both living and cadaver tails change with exposure duration. To make direct comparisons, the responses of both cadaver and living rat tails were examined on four different testing stations. The transfer function of each tail under a given contact force (2 N) was measured at each frequency in the one-third octave bands from 20 to 1000 Hz and used to calculate the mechanical system parameters of the tails. The transfer functions were also measured at different exposure durations to determine the time dependency of the response. Differences were observed in the vibration biodynamic responses between living and cadaver tails, but the general trends were similar. The biodynamic responses of both cadaver and living rat tails varied with exposure duration. [Description provided by NIOSH]
• Subjects:
  Laboratories Occupational Health Safety Vibration
• Keywords:
  Author Keywords: Hand-arm Vibration Biodynamics Hand-arm Vibration Syndrome Hand-transmitted Vibration HAVS Laboratory Animals Power Tools Rat-tail Vibration Model Vibration-induced White Finger Vibration Exposure
• ISSN:
  2571-631X
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  7
• Issue:
  3
• NIOSHTIC Number:
  nn:20070209
• Citation:
  Vibration 2024 Sep; 7(3):722-737
• Contact Point Address:
  Xueyan S. Xu, Physical Effects Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, 26505, USA
• Email:
  fze2@cdc.gov
• Federal Fiscal Year:
  2024
• Peer Reviewed:
  True
• Source Full Name:
  Vibration
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6d751b19f0bc356e3f82da583460e51b98adff8e6456240beeda59c1a845019e31ed2a51bc3c297d74dc48ec2ab5b90931d95039a557086e405669ab8934f34b
• Download URL:
  https://stacks.cdc.gov/view/cdc/208464/cdc_208464_DS1.pdf
• File Type:
  [PDF - 2.98 MB ]