A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure

Details

• Personal Author:
  Bazyka D ; Berrington de Gonzalez A ; Brenner AV ; Chumak VV ; Cullings HM ; Daniels, Robert D. ; French B ; Grant E ; Hamada N ; Hauptmann M ; Kendall GM ; Laurier D ; Lee C ; Lee WJ ; Linet MS ; Little MP ; Mabuchi K ; Morton LM ; Muirhead CR ; Preston DL ; Rajaraman P ; Richardson DB ; Sakata R ; Samet JM ; Simon SL ; Sugiyama H ; Wakeford R ; Zablotska LB
• Description:
  In this article we review the history of key epidemiological studies of populations exposed to ionizing radiation. We highlight historical and recent findings regarding radiation-associated risks for incidence and mortality of cancer and non-cancer outcomes with emphasis on study design and methods of exposure assessment and dose estimation along with brief consideration of sources of bias for a few of the more important studies. We examine the findings from the epidemiological studies of the Japanese atomic bomb survivors, persons exposed to radiation for diagnostic or therapeutic purposes, those exposed to environmental sources including Chornobyl and other reactor accidents, and occupationally exposed cohorts. We also summarize results of pooled studies. These summaries are necessarily brief, but we provide references to more detailed information. We discuss possible future directions of study, to include assessment of susceptible populations, and possible new populations, data sources, study designs and methods of analysis. [Description provided by NIOSH]
• Subjects:
  Environmental Exposure Epidemiology Neoplasms Occupational Exposure Occupational Health Safety
• Keywords:
  Cancer Rates Environmental Exposure Exposure Assessment Ionizing Radiation Mortality Studies Occupational Exposure
• ISSN:
  0033-7587
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  California ; Colorado ; Ohio ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 8 ; OSHA Region 9 ; Tennessee
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  WTCHP - World Trade Center Health Program
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  432-487
• Volume:
  202
• Issue:
  2
• NIOSHTIC Number:
  nn:20069913
• Citation:
  Radiat Res 2024 Aug; 202(2):432-487
• Contact Point Address:
  Mark P. Little, Radiation Epidemiology Branch, National Cancer Institute, 9609 Medical Center Drive, Bethesda, MD 20892-9778
• Email:
  mark.little@nih.gov
• Federal Fiscal Year:
  2024
• Peer Reviewed:
  True
• Source Full Name:
  Radiation Research
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:70d3f4c475c7b881a7a51d48ffaa3ff77c2ef8ec58b932d68121dfac813be4b02f2c4cb4b8b1391cf653bbf7f1c3d76ff97834b236fa49213cd913a96a7afa9b
• Download URL:
  https://stacks.cdc.gov/view/cdc/208239/cdc_208239_DS1.pdf
• File Type:
  [PDF - 876.56 KB ]