Microfluidic Integration of µPID on µcolumn for Ultracompact Micro-Gas Chromatography

Details

• Personal Author:
  Fan X ; Huang X ; Jeong S-Y ; Li W ; Nidetz R ; Sharma R ; Sivakumar AD ; Thota C ; Wu W ; Yang S ; Zhu H
• Description:
  Microfabricated gas chromatography (µGC) offers a powerful portable vapor analysis solution for various field applications. Here, we developed a microfluidically integrated architecture of a microfluidic photoionization detector (µPID) on a microfabricated column (µcolumn) via a silicon-on-insulator platform. By eliminating the off-chip interconnects, the microfluidically integrated column PID (iCPID) demonstrated a narrow peak width compared to the off-chip benchmark µPID. Furthermore, the iCPID sensitivity as a function of the bias voltage and temperature were characterized. Finally, an ultracompact (0.9 L, 0.9 kg), automated, and battery-operated µGC system without any benchtop components was constructed based on the iCPID. Rapid (2 min) isothermal separation of eight volatile compounds at room temperature was demonstrated. [Description provided by NIOSH]
• Subjects:
  Occupational Health Safety Volatile Organic Compounds
• Keywords:
  Analytical Instruments Author Keywords: Gas Chromatography Biomedical Engineering Detectors Gas Chromatography Gas Sensing GC Column Microfabrication Photo-ionization Detector Sensors VOCs Volatile Organic Compounds

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• ISSN:
  0925-4005
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Michigan ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  410
• NIOSHTIC Number:
  nn:20069543
• Citation:
  Sens Actuators B Chem 2024 Jul; 410:135717
• Contact Point Address:
  Xudong Fan, Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA
• Email:
  xsfan@umich.edu
• Federal Fiscal Year:
  2024
• Performing Organization:
  University of Michigan at Ann Arbor
• Peer Reviewed:
  True
• Start Date:
  20180901
• Source Full Name:
  Sensors and Actuators B: Chemical
• End Date:
  20220831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2fdd0eca09aa2dbdb8cf5099cbdb9ed3913d171c4e3a20ff79f0b0b71c411ef7637c85d8b1c20755e78e5433bc6cf876c18d44efecc91633245a7edf387bbe9a
• Download URL:
  https://stacks.cdc.gov/view/cdc/207963/cdc_207963_DS1.pdf
• File Type:
  [PDF - 4.91 MB ]