Design and Evaluation of a High-Flowrate Nanoparticle Respiratory Deposition (NRD) Sampler

Details

• Personal Author:
  Gonzalez-Pech NI ; Grassian VH ; Park JH ; Peters TM ; Stebounova LV ; Szabo McCollom TI
• Description:
  A high-flow (10 L/min) nanoparticle respiratory deposition (NRD) sampler was designed and evaluated to achieve reduced limits of quantification (LOQs) for metal nanoparticles. The high-flow NRD consists of an inlet, impactor stage, diffusion stage, and a final filter. An impactor stage with 12 nozzles was designed from theory to achieve a cut-off diameter of 300 nm at 50% particle collection efficiency (d50). Various depths of 37-mm-diameter polyurethane foam cylinders were tested for the diffusion stage to obtain a collection efficiency curve similar to the deposition of nanoparticles in the human respiratory tract, known as the nanoparticulate matter (NPM) criterion. The objective for the final filter was a collection efficiency of near 100% with minimal pressure drop. The collection efficiencies by size and pressure drops were measured for all NRD sampler components. The final design of the impactor stage nozzle achieved a d50 of 305 nm. The collection efficiency for the diffusion stage with a depth of 7 cm when adjusted for presence of the impactor was the closest to the NPM curve with a R2 value of 0.96 and d50 of 43 nm. Chemical analysis of the metal content for foam affirmed that the high-flow NRD sampler required less sampling time to meet metal LOQs than the 2.5 L/min NRD sampler. The final filter with a modified support pad had a collection efficiency near 100%. The overall pressure drop of the sampler of 8.5 kPa (34 in. H2O) could not be handled by commercial personal sampling pumps. Hence the high-flow NRD sampler can be used as an area sampler or without the final filter for collection of nanoparticles. [Description provided by NIOSH]
• Subjects:
  Aerosols Metals Occupational Health Particulate Matter Safety
• Keywords:
  Aerosol Sampling Author Keywords: Collection Efficiency Deposition Diffusion Diffusion Stage Exposure Filters Impactor Nanoparticle Nanoparticle High-flow Sampler Nanoparticles Nanotechnology Particulates Pressure Drop Respiratory Respiratory Deposition Curve Sampler Samplers

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• ISSN:
  0021-8502
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Indiana ; Iowa ; OSHA Region 5 ; OSHA Region 7 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  72-79
• Volume:
  134
• NIOSHTIC Number:
  nn:20068578
• Citation:
  J Aerosol Sci 2019 Aug; 134:72-79
• Contact Point Address:
  Thomas M. Peters, 145 N Riverside Drive, S325 CPHB, Department of Occupational and Environmental Health, University of Iowa, Iowa City, IA, 52242, USA
• Email:
  thomas-m-peters@uiowa.edu
• Federal Fiscal Year:
  2019
• Performing Organization:
  University of Iowa, Iowa City
• Peer Reviewed:
  True
• Start Date:
  20130901
• Source Full Name:
  Journal of Aerosol Science
• End Date:
  20180831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d7912e93936073863a25e6b34fad0e571a1391fc91700e78f27d5e24dd315ab3ea3a37ca29afb990379684a1302b9a48db224a2d4fb747c26a58d007fa907549
• Download URL:
  https://stacks.cdc.gov/view/cdc/207184/cdc_207184_DS1.pdf
• File Type:
  [PDF - 1.13 MB ]