Mortality Among Employees of a Perfluorooctanoic Acid Production Plant

Details

• Personal Author:
  Gilliland FD ; Mandel JS
• Description:
  A study was conducted on the mortality rates of workers exposed to perfluorooctanoic-acid (335671) (PFOA). Workers at a chemical factory that produced PFOA were categorized as exposed or nonexposed, and the numbers of cause specific deaths were compared to expected numbers. The standardized mortality ratios for all causes of death for all women employees as well as for exposed women employees were significantly lower than expected. Similar results were seen for male employees. No associations were seen for male employees between any cause of death and length of employment. A standardized mortality ratio of 2.03 for prostate cancer was seen for exposed males compared with 0.58 for nonexposed males. A weak but significant positive association was seen between exposure and prostate cancer risk and the risk increased with length of employment. A positive association was seen as well between age at first employment and prostate cancer mortality. [Description provided by NIOSH]
• Subjects:
  Fluorine Manufacturing And Industrial Facilities Mortality Neoplasms Occupational Exposure Occupational Health Safety Staff Development Surface-Active Agents Urogenital Diseases Urogenital System

  More +
• Keywords:
  Chemical-industry-workers Fluorine-compounds JOCMA7 Mortality-rates NIOSH-Grant NIOSH-Publication Occupational-exposure Prostate-cancer Surfactants Training
• DOI:
  https://doi.org/10.1097/00043764-199309000-00020
• ISSN:
  0096-1736
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Minnesota ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  35
• Issue:
  9
• NIOSHTIC Number:
  nn:00217002
• Citation:
  J Occup Med 1993 Sep; 35(9):950-954
• CAS Registry Number:
  Perfluorooctanoic acid (CAS RN 335-67-1)
• Federal Fiscal Year:
  1993
• Performing Organization:
  University of Minnesota of Mnpls-St Paul, Minneapolis, Minnesota
• Peer Reviewed:
  True
• Start Date:
  19770930
• End Date:
  19940630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/205137/cdc_205137_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]