Monitoring peach harvest workers exposed to azinphosmethyl residues in Sutter County, California, 1991

Details

• Personal Author:
  Hernandez B ; Krieger R ; Margetich S ; Schneider F ; Spencer J ; Steenland, Kyle ; Wilson B
• Description:
  Field worker exposure to azinphosmethyl (86500) residues during peach harvest was evaluated via dermal dosimeters and urine and blood analyses. Workers entered orchards 51 days after pesticide application and worked in treated fields for ten of the next 17 days; measurements included foliar residues, urinary alkylphosphate metabolites, butyrylcholinesterase (BChE), acetylcholinesterase (AChE), and dermal residues. Dislodgeable foliar residues ranged from 0.82 to 1.72 micrograms per square centimeter over the three week study period. The mean daily dermal exposure for three consecutive monitoring days was approximately 32 milligrams. While BChE values of exposed harvesters were comparable to those of minimally exposed sorters, the exposed group had significantly lower AChE values in postexposure blood draws by three different testing methods; no significant differences were noted in preexposure blood draws. Exposed workers also experienced a 10 to 20% decrease in AChE values over the 3 week exposure period, while values increased or remained constant for sorters. Urinary metabolite excretion increased over sequential monitoring days in both sorters and harvesters. AChE was significantly inversely correlated with urinary phosphates. High correlations were observed between field and laboratory measurements of AChE. Findings were consistent with literature reports of an AChE, but not BChE, effect of azinphosmethyl. [Description provided by NIOSH]
• Subjects:
  Agriculture Cholinesterase Inhibitors Hematologic Tests Insecticides Occupational Exposure Occupational Health Safety Skin Urine
• Keywords:
  Agricultural-workers Author Keywords: Alkylphosphates Azinphosmethyl Biological-monitoring Blood-analysis Cholinesterase Cholinesterase-inhibitors Exposure Monitor NIOSH-Author Occupational-exposure Pesticide-residues Skin-exposure Urinalysis

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• ISSN:
  0091-6765
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  California ; Ohio ; OSHA Region 10 ; OSHA Region 5 ; OSHA Region 9 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  102
• Issue:
  6
• NIOSHTIC Number:
  nn:00222062
• Citation:
  Environ Health Perspect 1994 Jun; 102(6-7):580-585
• Contact Point Address:
  F. Schneider, Department of Pesticide Regulation, California EPA, 1020 N Street, Sacramento, CA 95814 USA
• CAS Registry Number:
  Azinphos-methyl (CAS RN 86-50-0)
• Federal Fiscal Year:
  1994
• Performing Organization:
  University of California - Davis
• Peer Reviewed:
  True
• Start Date:
  19900930
• Source Full Name:
  Environmental Health Perspectives
• End Date:
  20020929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:91665d3b813fac13a66dd6ad6339785c6f4c1a426cf443b9ca1df1d9aa0be7cf55961fd7735c5fbe999af192a07ca47158aa19ede5b8f95c12edad6f5f68642a
• Download URL:
  https://stacks.cdc.gov/view/cdc/205130/cdc_205130_DS1.pdf
• File Type:
  [PDF - 1.72 MB ]