Optimized Probability Sampling of Study Sites to Improve Generalizability in a Multisite Intervention Trial

Details

• Journal Article:
  Preventing Chronic Disease (PCD)
• Personal Author:
  Samuel-Hodge, Carmen D. ; Kraschnewski, Jennifer L. ; Keyserling, Thomas C. ; Bangdiwala, Shrikant I. ; Gizlice, Ziya ; Garcia, Beverly A. ; Johnston, Larry F. ; Gustafson, Alison ; Petrovic, Lindsay ; Glasgow, Russell E.
• Description:
  Introduction
  
  Studies of type 2 translation, the adaption of evidence-based interventions to real-world settings, should include representative study sites and staff to improve external validity. Sites for such studies are, however, often selected by convenience sampling, which limits generalizability. We used an optimized probability sampling protocol to select an unbiased, representative sample of study sites to prepare for a randomized trial of a weight loss intervention.
  
  Methods
  
  We invited North Carolina health departments within 200 miles of the research center to participate (N = 81). Of the 43 health departments that were eligible, 30 were interested in participating. To select a representative and feasible sample of 6 health departments that met inclusion criteria, we generated all combinations of 6 from the 30 health departments that were eligible and interested. From the subset of combinations that met inclusion criteria, we selected 1 at random.
  
  Results
  
  Of 593,775 possible combinations of 6 counties, 15,177 (3%) met inclusion criteria. Sites in the selected subset were similar to all eligible sites in terms of health department characteristics and county demographics.
  
  Conclusion
  
  Optimized probability sampling improved generalizability by ensuring an unbiased and representative sample of study sites.
  
  
• Subjects:
  Adult Female Government Agencies Health Personnel Health Services Health Services Research Humans Middle Aged Original Research Overweight Poverty Sampling Studies State Government Weight Loss

  More +
• Source:
  Prev Chronic Dis. 7(1).
• ISSN:
  1545-1151
• Pubmed ID:
  20040225
• Pubmed Central ID:
  PMC2811505
• Document Type:
  Journal Article
• Funding:
  5R18DP001144-02/DP/NCCDPHP CDC HHS/United States ; 5T32 PE14001-20/PE/BHP HRSA HHS/United States ; U48/DP000059/DP/NCCDPHP CDC HHS/United States
• Place as Subject:
  North Carolina
• Location:
  North America
• Volume:
  7
• Issue:
  1
• Collection(s):
  Preventing Chronic Disease
• Main Document Checksum:
  urn:sha-512:da120a27020afcca95c839d42338d5dfa0321e489d43390e17132d667d63d25f6c585919cafdfae77ee19d99c33eb914f393d766503e34459b766f2e80b0f220
• Download URL:
  https://stacks.cdc.gov/view/cdc/20423/cdc_20423_DS1.pdf
• File Type:
  [PDF - 408.35 KB ]