Response to Goodman et al

Details

• Personal Author:
  Daniels, Robert D. ; Fent, Kenneth W. ; Pinkerton LE ; Yiin JH
• Description:
  We thank the Journal for providing us the opportunity to respond to the letter from Goodman et al. [2017 Feb; 60(2):221-222] regarding the conclusions of our mortality study among toluene diisocyanate (TDI)-exposed workers [Pinkerton et al., 2016 Aug; 59(8):630-643]. Goodman et al. conclude that our study does not provide support for the carcinogenicity of TDI. We acknowledge that proof of a causal association between occupational exposure and cancer cannot be achieved by our study. Nonetheless, we contend that our findings add to a growing body of evidence of a causal association between TDI exposure and cancer and that dermal exposures could play an important role. [Description provided by NIOSH]
• Subjects:
  Isocyanates Lung Lung Diseases Mortality Neoplasms Occupational Health Respiratory System Respiratory Tract Diseases Safety Skin Toluene

  More +
• Keywords:
  Cancer Dermal Exposures Diisocyanates Lung Cancer Mortality Data Mortality Rates Mortality Studies Skin Exposure
• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  223-225
• Volume:
  60
• Issue:
  2
• NIOSHTIC Number:
  nn:20049112
• Citation:
  Am J Ind Med 2017 Feb; 60(2):223-225
• Contact Point Address:
  Lynne E. Pinkerton, MD, MPH, Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, 1090 Tusculum Ave, R-15, Cincinnati, OH 45226
• Email:
  lep5@cdc.gov
• CAS Registry Number:
  Toluene diisocyanate (CAS RN 26471-62-5)
• Federal Fiscal Year:
  2017
• Peer Reviewed:
  False
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2ab3086c730b5f9c3a8a0534f6194980e43f017267e153f641c790d24aba7c63ec27ec38d65b54de6115e15f38044bb0440547dfddcabce7550391de35b3630f
• Download URL:
  https://stacks.cdc.gov/view/cdc/203680/cdc_203680_DS1.pdf
• File Type:
  [PDF - 42.68 KB ]