Association between sleep deficiency and cardiometabolic disease: implications for health disparities

Details

• Personal Author:
  Knutson KL ; Rangaraj VR
• Description:
  Background: Cardiometabolic diseases, which include obesity, diabetes, hypertension, and cardiovascular disease, are associated with reduced quality of life and reduced life expectancy. Unfortunately, there are racial/ethnic and socioeconomic disparities associated with these diseases such that minority populations, such as African Americans and Hispanics, and those of lower socioeconomic status, experience a greater burden. Several reports have indicated that there are differences in sleep duration and quality that mirror the disparities in cardiometabolic disease. The goal of this paper is to review the association between sleep and cardiometabolic disease risk because of the possibility that suboptimal sleep may partially mediate the cardiometabolic disease disparities. Methods: We review both experimental studies that have restricted sleep duration or impaired sleep quality and examined biomarkers of cardiometabolic disease risk, including glucose metabolism and insulin sensitivity, appetite regulation and food intake, and immune function. We also review observational studies that have examined the association between habitual sleep duration and quality, and the prevalence or risk of obesity, diabetes, hypertension, and cardiovascular disease. Conclusion: Many experimental and observational studies do support an association between suboptimal sleep and increased cardiometabolic disease risk. [Description provided by NIOSH]
• Subjects:
  Biomarkers Blood Cardiovascular Diseases Cardiovascular System Epidemiology Healthcare Disparities Hematologic Diseases Immune System Men Occupational Health Race Factors Risk Assessment Risk Factors Safety Sleep Sleep Initiation And Maintenance Disorders Women

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• Keywords:
  Author Keywords: Diabetes Blood Sugar Disorders Cardiac Function Cardiovascular-disease Etiology Health Disparities Humans Hypertension Immune Reaction Inflammation Metabolic Disorders Obesity Physiopathology Quality Of Life Racial Factors Risk-analysis Risk Factors Sleep-deprivation Sleep-disorders Socioeconomics

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• ISSN:
  1389-9457
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Illinois ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  19-35
• Volume:
  18
• NIOSHTIC Number:
  nn:20049101
• Citation:
  Sleep Med 2016 Feb; 18:19-35
• Contact Point Address:
  Kristen L. Knutson, Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, 5841 S Maryland Ave, MC6076, Chicago, IL 60637, USA
• Email:
  kknutson@medicine.bsd.uchicago.edu
• Federal Fiscal Year:
  2016
• Performing Organization:
  University of Chicago
• Peer Reviewed:
  True
• Start Date:
  20090901
• Source Full Name:
  Sleep Medicine
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:bb1fe5a9ed0600aefe6fb281d5713f54bb2309384953798193b6ef7b0796308dbc91986541f4dc7829016d24e78a44b5332161031b8d3f3eac19e139445be7e3
• Download URL:
  https://stacks.cdc.gov/view/cdc/203673/cdc_203673_DS1.pdf
• File Type:
  [PDF - 615.82 KB ]