Environmental and occupational particulate matter exposures and ectopic heart beats in welders

Details

• Personal Author:
  Cavallari JM ; Christiani, David C. ; Eisen EA ; Fang SC ; Mittleman MA
• Description:
  Objectives: Links between arrhythmias and particulate matter exposures have been found among sensitive populations. We examined the relationship between personal particulate matter ≤ 2.5 microm aerodynamic diameter (PM2.5) exposures and ectopy in a panel study of healthy welders. Methods: Simultaneous ambulatory ECG and personal PM2.5 exposure monitoring with DustTrak Aerosol Monitor was performed on 72 males during work and non-work periods for 5.90 h (median 40 h). ECGs were summarised hourly for supraventricular ectopy (SVE) and ventricular ectopy (VE). PM2.5 exposures both work and non-work periods were averaged hourly with lags from 0 to 7 h. Generalised linear mixed-effects models with a random participant intercept were used to examine the relationship between PM2.5 exposure and the odds of SVE or VE. Sensitivity analyses were performed to assess whether relationships differed by work period and among current smokers. Results: Participants had a mean (SD) age of 38 (11) years and were monitored over 2993 person-hours. The number of hourly ectopic events was highly skewed with mean (SD) of 14 (69) VE and 1 (4) SVE. We found marginally significant increases in VE with PM2.5 exposures in the sixth and seventh hour lags, yet no association with SVE. For every 100 microg/m3 increase in sixth hour lagged PM2.5, the adjusted OR (95% CI) for VE was 1.03 (1.00 to 1.05). Results persisted in work or non-work exposure periods and non-smokers had increased odds of VE associated with PM2.5 as compared with smokers. Conclusions: A small increase in the odds of VE with short-term PM2.5 exposure was observed among relatively healthy men with environmental and occupational exposures. [Description provided by NIOSH]
• Subjects:
  Cardiovascular System Dust Electrocardiography Environmental Exposure Men Metals Occupational Exposure Occupational Health Particulate Matter Risk Assessment Risk Factors Safety Smokers Welding

  More +
• Keywords:
  Cardiac-function Cardiovascular Function Cardiovascular Function Tests Environmental-exposure Exposure-levels Exposure Assessment Heart Heart-rate Humans Metal Dusts Metallic Dusts Occupational Exposure Particle Aerodynamics Particle Diameter Particulate Dust Particulates Risk Factors Smoking Welders Welding-industry

  More +
• ISSN:
  1351-0711
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Connecticut ; Massachusetts ; OSHA Region 1 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  435-441
• Volume:
  73
• Issue:
  7
• NIOSHTIC Number:
  nn:20047850
• Citation:
  Occup Environ Med 2016 Jul; 73(7):435-441
• Contact Point Address:
  Dr Jennifer M Cavallari, Division of Occupational and Environmental Medicine, UConn Health Center, Farmington, CT 06032, USA
• Email:
  cavallari@uchc.edu
• Federal Fiscal Year:
  2016
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Occupational and Environmental Medicine
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f21f82c1eb0c4d7cf0734a28081016588701e8a0ab8cd5fc633473b2abe257aeee8cd5e42381be101048aced8993af5b35ac6534e7476136ee2c359eab2d67bb
• Download URL:
  https://stacks.cdc.gov/view/cdc/202810/cdc_202810_DS1.pdf
• File Type:
  [PDF - 372.51 KB ]