Hyperspectral microscopy as an analytical tool for nanomaterials

Details

• Personal Author:
  Brenner SA ; Neu-Baker NM ; Roth GA ; Tahiliani S
• Description:
  Hyperspectral microscopy is an advanced visualization technique that combines hyperspectral imaging with state-of-the-art optics and computer software to enable the rapid identification of materials at the micro- and nanoscales. Achieving this level of resolution has traditionally required time-consuming and costly electron microscopy techniques. While hyperspectral microscopy has already been applied to the analysis of bulk materials and biologicals, it shows extraordinary promise as an analytical tool to locate individual nanoparticles and aggregates in complex samples through rapid optical and spectroscopic identification. This technique can be used to not only screen for the presence of nanomaterials, but also to locate, identify, and characterize them. It could also be used to identify a subset of samples that would then move on for further analysis via other advanced metrology. This review will describe the science and origins of hyperspectral microscopy, examine current and emerging applications in life science, and examine potential applications of this technology that could improve research efficiency or lead to novel discoveries. [Description provided by NIOSH]
• Subjects:
  Occupational Health Safety
• Keywords:
  Analytical Instruments Analytical Processes Microscopy Nano-objects Nanomaterials Nanotechnology
• ISSN:
  1939-0041
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  7
• Issue:
  4
• NIOSHTIC Number:
  nn:20047640
• Citation:
  Wiley Interdiscip Rev. Nanomed Nanobiotechnol 2015 Jul-Aug; 7(4):565-579
• Contact Point Address:
  Sara A. Brenner, College of Nanoscale Science, Nanobioscience Constellation, State University of New York (SUNY) Polytechnic Institute, New York, NY, USA
• Email:
  sbrenner@sunycnse.com
• Federal Fiscal Year:
  2015
• Performing Organization:
  State University of New York at Albany
• Peer Reviewed:
  True
• Start Date:
  20120901
• Source Full Name:
  Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
• End Date:
  20150828
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c2daff59eb750e58db6207587a51f0f3f8393ae908d3dfb2572354decc4231a8253901477f7667cbc35bee240e1959e0e04ffcd6280681a58b23f14d04a3c231
• Download URL:
  https://stacks.cdc.gov/view/cdc/202654/cdc_202654_DS1.pdf
• File Type:
  [PDF - 807.19 KB ]