Polybrominated diphenyl ethers (PBDE) and their hydroxlyated and methoxylated derivatives in seafood and dust collected from the Puget Sound, Washington Region

Details

• Personal Author:
  Cade S ; Kuo L-J ; Schultz I
• Description:
  The most important routes of human exposure to PBDEs are from contaminated food and contact with dust found in households and workplaces. Structurally related derivatives of PBDEs are the hydroxylated (OH-PBDEs) and methoxylated forms (MeO-PBDEs). Humans can metabolize some PBDEs into the hydroxylated forms, which is a concern due to greater health risks associated with OH-PBDEs. However, certain OH-PBDEs and MeO-PBDEs are also marine natural products and it is unclear although likely, that marine fish and shellfish, which bioaccumulate these compounds serve as a vector for human exposures. In this study, we measured approximately 30 different PBDE, OH-PBDEs and MeO-PBDEs in edible shellfish and finfish collected or purchased from seafood markets and restaurants located in the Puget Sound region of Washington State. We also measured 12 common PBDE congeners including PBDE-209 in dust samples collected from electronic waste (E-waste) recycling businesses, non-E-waste businesses and private homes. The focus on E-waste recycling was due to concerns that it's an occupation that may expose workers to dust with enriched levels of PBDEs. Results from the dust analysis indicated the predominant PBDE congeners measured were: PBDE-209 > PBDE-153 >> PBDE-183 > PBDE- 47 > PBDE-99 > PBDE-100 > PBDE-154, 138. PBDE-17,28,66,71 were very low or undetectable. PBDE-209 was detected in all dust samples and exceeded 300 ug/g at one E-waste site. The most notable differences in the PBDE profiles from E-waste vs. non-E-waste dust was associated with PBDE-209 and PBDE-153, which were 15 - 1000 times higher at E-waste sites. [Description provided by NIOSH]
• Subjects:
  Dust Electrical Equipment And Supplies Environmental Exposure Environmental Pollution Hazardous Substances Hazardous Waste Hunting Occupational Health Recycling Safety Toxicology

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• Keywords:
  Contaminated-food Dust-exposure Dusts Dust Sampling Electronic Equipment Environmental Contamination Environmental Exposure Exposure Assessment Exposure Levels Fishing-industry Food Hazardous Waste Health Effects Humans Hydroxylation Reactions Metabolic Activation Polybrominated Diphenyl Ethers Waste Treatment

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• ISSN:
  1096-6080
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  Louisiana ; OSHA Region 10 ; OSHA Region 6 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  150
• Issue:
  1
• NIOSHTIC Number:
  nn:20047639
• Citation:
  Toxicologist 2016 Mar; 150(1):163
• Federal Fiscal Year:
  2016
• Performing Organization:
  Battelle Pacific Northwest Laboratories
• Peer Reviewed:
  False
• Start Date:
  20130901
• Source Full Name:
  The Toxicologist. Society of Toxicology 55th Annual Meeting and ToxExpo, March 13-17, 2016, New Orleans, Louisiana
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:32730380e8e7d6f8c214fc18066c18b0a0d1282658bd2e34241540d7ad54075793e0fb171aea7472caf617be71ea6476e04745bb6393f660750bf8019f209e0b
• Download URL:
  https://stacks.cdc.gov/view/cdc/202653/cdc_202653_DS1.pdf
• File Type:
  [PDF - 442.33 KB ]