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GC-on-chip: integrated column and photoionization detector



Details

  • Personal Author:
  • Description:
    This paper reports a unique GC-on-chip module comprising a monolithically integrated semi-packed micro separation column (microSC) and a highly sensitive micro helium discharge photoionization detector (microDPID). While semi-packed microSC with atomic layer deposited (ALD) alumina as a stationary phase provides high separation performance, the microDPID implemented for the first time in a silicon-glass architecture inherits the desirable features of being universal, non-destructive, low power consumption (1.4 mW), and responsive. The integrated chip is 1.5 cm times 3 cm in size and requires a two-mask fabrication process. Monolithic integration alleviates the need for transfer lines between the column and the detector which improves the performance of the individual components with overall reduced fabrication and implementation costs. The chip is capable of operating under the isothermal as well as temperature and flow programming conditions to achieve rapid chromatographic analysis. The chip performance was investigated with two samples: 1) a multi-analyte gas mixture consisting of eight compounds ranging from 98 degrees C to 174 degrees C in boiling point and 2) a mixture containing higher alkanes (C9-C12). Our experiments indicate that the chip is capable of providing rapid chromatographic separation and detection of these compounds (<1 min) through the optimization of flow and temperature programming conditions. The GC-on-chip demonstrated a minimum detection limit of approximately 10 pg which is on a par with the widely used destructive flame ionization detector (FID). [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • ISSN:
    1473-0197
  • Document Type:
    Text
  • Funding:
    Grant
  • Genre:
    Journal Article
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Volume:
    15
  • Issue:
    7
  • NIOSHTIC Number:
    nn:20046642
  • Citation:
    Lab Chip 2015 Apr; 15(7):1748-1758
  • Contact Point Address:
    M. Agah, VT MEMS Lab, Bradley Department of Electrical and Computer Engineering, Virginia Tech, Blacksburg, Virginia 24061, USA
  • Email:
    agah@vt.edu
  • Federal Fiscal Year:
    2015
  • Performing Organization:
    Virginia Polytechnic Institute and State University
  • Peer Reviewed:
    True
  • Start Date:
    20120701
  • Source Full Name:
    Lab on a Chip
  • End Date:
    20150630
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:0bfc0b86f4f39c1cde716068ce71107b3ce48794fa36dd295c627b825325902c6559e0e0a2095010f36841d4325a437c1e0fb6df385e49290c8f24dc66ba5456
  • Download URL:
  • File Type:
    Filetype[PDF - 5.36 MB ]
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