Comment on Farsalinos et al., "Evaluation of electronic cigarette liquids and aerosol for the presence of selected inhalation toxins.

Details

• Personal Author:
  Cummings, Kristin J. ; Dankovic, David A. ; Hubbs, Ann F. ; Kreiss, Kathleen ; McKernan, Lauralynn T. ; Park RM
• Description:
  We read with great interest the recent publication, "Evaluation of electronic cigarette liquids and vapour for the presence of selected inhalation toxins." We are particularly grateful to the authors for recognizing the high rate of chronic obstructive pulmonary disease and of bronchiolitis, specifically, in smokers and for measuring the concentrations of diacetyl (DA) and acetyl propionyl (AP, also known as 2,3-pentanedione) in electronic cigarette (e-cigarette) liquids and aerosols. However, we would like to clarify two issues: 1) The NIOSH draft document, Criteria for a Recommended Standard: Occupational Exposure to Diacetyl and 2,3-Pentanedione, proposes recommended exposure limits (RELs) to reduce the risk of respiratory impairment (decreased lung function) and the severe irreversible lung disease, constrictive bronchiolitis obliterans, associated with occupational exposure to these chemicals. As noted by Farsalinos and co-workers in their limitations section, it is not intended to establish "safe" exposure concentrations for consumers or the general public. The exposure comparisons between e-cigarette users and traditional cigarette smokers and workers use values that are not widely accepted. [Description provided by NIOSH]
• Subjects:
  Aerosols Electrical Equipment And Supplies Hazardous Substances Inhalation Exposure Lung Diseases Occupational Health Respiratory Tract Diseases Safety Smokers Solvents Tobacco Products

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• Keywords:
  Cigarette-smoking Electronic-components Electronic-devices Inhalants Lung-disorders Pulmonary-system-disorders Respiratory-system-disorders Smoking Toxic-vapors Toxins Vapors

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• ISSN:
  1462-2203
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division ; DRDS - Division of Respiratory Disease Studies ; EID - Education and Information Division ; RHD - Respiratory Health Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  17
• Issue:
  10
• NIOSHTIC Number:
  nn:20045704
• Citation:
  Nicotine Tob Res 2015 Oct; 17(10):1288-1289
• Contact Point Address:
  Ann F. Hubbs, DVM, PhD, DACVP, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Rd. Morgantown, WV 26505
• Email:
  ahubbs@cdc.gov
• CAS Registry Number:
  2,3-Pentanedione (CAS RN 600-14-6) ; Butanedione (CAS RN 431-03-8)
• Federal Fiscal Year:
  2016
• NORA Priority Area:
  Manufacturing
• Peer Reviewed:
  False
• Source Full Name:
  Nicotine & Tobacco Research
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:cfaf2cb9a76c6dbc06ff538532af772e472cef44ce89b1e5a281bb488a8a63fac511052eb68a4baaa069cbdd70556534eab9b3c7b2f87aff6157680abf615947
• Download URL:
  https://stacks.cdc.gov/view/cdc/201019/cdc_201019_DS1.pdf
• File Type:
  [PDF - 475.13 KB ]