Isocyanates and human health: multistakeholder information needs and research priorities

Details

• Personal Author:
  Comai A ; Ellison GL ; Hakkinen PJ ; Harber P ; Holland J ; Lockey, James E. ; Pfahles-Hutchens A ; Redlich CA ; Streicher R ; Utell M ; White M
• Description:
  Objectives: To outline the knowledge gaps and research priorities identified by a broad base of stakeholders involved in the planning and participation of an international conference and research agenda workshop on isocyanates and human health held in Potomac, Maryland, in April 2013. Methods: A multimodal iterative approach was used for data collection including preconference surveys, review of a 2001 consensus conference on isocyanates, oral and poster presentations, focused break-out sessions, panel discussions, and postconference research agenda workshop. Results: Participants included representatives of consumer and worker health, health professionals, regulatory agencies, academic and industry scientists, labor, and trade associations. Conclusions: Recommendations were summarized regarding knowledge gaps and research priorities in the following areas: worker and consumer exposures; toxicology, animal models, and biomarkers; human cancer risk; environmental exposure and monitoring; and respiratory epidemiology and disease, and occupational health surveillance. [Description provided by NIOSH]
• Subjects:
  Animals Biomarkers Epidemiology Isocyanates Neoplasms Occupational Health Respiratory Tract Diseases Risk Assessment Risk Factors Safety
• Keywords:
  Cancer Exposure-limits Models Monitoring-systems Respiratory-system-disorders Risk-factors
• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Arizona ; Connecticut ; District of Columbia ; Maryland ; Michigan ; New York ; Ohio ; OSHA Region 1 ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  44-51
• Volume:
  57
• Issue:
  1
• NIOSHTIC Number:
  nn:20045501
• Citation:
  J Occup Environ Med 2015 Jan; 57(1):44-51
• Contact Point Address:
  James E. Lockey, MD, MS, Department of Environmental Health, Division of Occupational and Environmental Medicine, University of Cincinnati College of Medicine, 3223 Eden Ave, Cincinnati, OH 45267
• Email:
  lockeyje@ucmail.uc.edu
• Federal Fiscal Year:
  2015
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:cdde2d78d4c5e34cdf59bbeaa582fc50171f8d1e7c70792964583a635fc40e133da3c9adcd41b94302ddef7ae20432ad3f3e3311498562e3743e2fbfd92b77c5
• Download URL:
  https://stacks.cdc.gov/view/cdc/200900/cdc_200900_DS1.pdf
• File Type:
  [PDF - 117.32 KB ]