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Blue-enriched versus white light for circadian phase delays



Details

  • Personal Author:
  • Description:
    The human circadian system is most sensitive to short wavelength (blue) light. We previously found that bright blue-enriched light produced larger phase advances than bright white light, when sleep/dark was advanced. This study compared the magnitude of phase delays induced by bright blue-enriched light and bright white light, when sleep/dark was delayed. Five 15-minute intermittent light pulses interspersed by 45 minutes of normal room light were delivered on each of two consecutive nights, from 00:45 to 05:00, to coincide with the delay portion of the PRC. Subjects received either blue-enriched light (17,000K, n=10) or white light, (5,095K, n=12). Subjects were exposed to similar luminance from the blue-enriched and white lamps (approximately 3900 vs approximately 3500 lux), but more total photons (4.6 vs 2.9 x 1015 photons/cm2/sec), and nearly 3 times as many photons in the blue (400-490nm) range (2.0 x 1015 vs 7.4 x 1014 photons/cm2/sec) from the blue-enriched lamps. The dim light melatonin onset (DLMO) and offset (DLMOff) were assessed before and after the light pulses. Mean (+/- SD) phase delays for the white and blue groups were 3.2 +/- 1.3 and 3.2 +/- 1.4 hours for the DLMO, and 3.6 +/- 1.6 and 1.4 +/- 1.5 hours for the DLMOff. Thus, the blueenriched and white light delayed the DLMO a similar amount, while the white light delayed the DLMOff significantly more. These surprising results will be discussed in terms of putative morning and evening oscillators. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • Publisher:
    Society for Research on Biological Rhythm
  • Document Type:
    Text
  • Funding:
    Grant
  • Genre:
    Abstract or Summary
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • NIOSHTIC Number:
    nn:20045466
  • Citation:
    Proceedings of the 10th meeting of the Society for Research on Biological Rhythms, May 21-25, 2006, Sandestin, Florida. Urbana, IL: Society for Research on Biological Rhythms, 2006 May; :131
  • Federal Fiscal Year:
    2006
  • Performing Organization:
    Rush University Medical Center, Chicago, Illinois
  • Peer Reviewed:
    False
  • Start Date:
    19990930
  • Source Full Name:
    Proceedings of the 10th meeting of the Society for Research on Biological Rhythms, May 21-25, 2006
  • End Date:
    20090430
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:dc613fdceba70f6c7a6ea2a119587ca1df4ab5fbb0749c6b73d520bf5469c44c2a66e81b20363691a222e896d3c869bcbbcfc5447a7645bcb06c8d18d0af5b70
  • Download URL:
  • File Type:
    Filetype[PDF - 69.52 KB ]
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